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Q: Function and structure of tissue plasminogen activator?
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What is Streptokinase and tissue-type plasminogen activator used for?

Streptokinase and tissue-type plasminogen activator are used for:


What is Streptokinase and tissue-type plasminogen activator are used for?

Streptokinase and tissue-type plasminogen activator are used for:


What is the duration of action of tissue plasminogen activator?

15 minutes.


Tissue plasminogen activator is administered to?

dissolve damaging blood clots


What is the treatments of stroke?

aspirin or a machine called tissue plasminogen activator.


What enzyme breaks up a blood clot in the heart?

Tissue plasminogen activator.


Which substance binds strongly to fibrin and dissolves clots that have caused heart attacks?

Tissue plasminogen activator


What Is administered a few hours after a heart attack or stroke to dissolve the damaging blood clots?

Tissue Plasminogen Activator


What is the difference between the mechanisms of action of streptokinase and tissue plasminogen activator in treating thrombosis?

Both are thrombolyltic drugs. Streptokinase binds to the active complex. It promotes the cleavage of the Arg/Val bond of plasminogen leading to the formation of plasmin. The plasmin then breaks down the matrix of the thrombus. A tissue plasminogen activator is alteplase. It binds to fibrin-rich clots and cleaves the Arg/Val bond of plasminogen to produce plasmin. The plasmin then breaks down the matrix of the thrombus.


What is alteplase?

Alteplase is the trade name for recombinant tissue plasminogen activator (r-tPA), a medication given to certain patients with ischemic stroke, pulmonary embolus, or myocardial infarction.


What has the author Charla K Triplett written?

Charla K. Triplett has written: 'A model system to study the effects of methylglyoxal on the yield and quality of tissue plasminogen activator produced by CHO cells' -- subject(s): Glyoxalase, Microbial toxins


What causes a blood clot to break up?

In the body's natural systems, tissue plasminogen activator or tPA attaches itself to the clot and breaks it down by plasmin fibrinolysis. This is done artificially (thrombolysis) using drugs such as streptokinase, urokinase, or recombinant tPA formulations.