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Genetic recombination is a major factor contributing to cell-mediated immunity. Different B cells and T cells are able to recognize a wide variety of targets because of the genetic recombination they undergo in developmental stages.

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9y ago

Genetic recombination generates diversity during the development stage. This is the time in which different B and T cells are able to recognize their targets.

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Q: Genetic recombination generates diversity in what part of the immune system?
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What stopped the bubonic plague disease from killing everyone?

Genetic diversity - some persons were naturally immune.


What is recombination?

Genetic recombination is the process by which a strand of genetic material (usually DNA; but can also be RNA) is broken and then joined to a different DNA molecule. In eukaryotes recombination commonly occurs during meiosis as chromosomal crossover between paired chromosomes. This process leads to offspring having different combinations of genes from their parents and can produce new chimeric alleles.Genetic recombination is the process by which two DNA molecules exchange genetic information, resulting in the production of a new combination of alleles. In eukaryotes, genetic recombination during meiosis can lead to a novel set of genetic information that can be passed on to progeny. Most recombination is naturally occurring. During meiosis in eukaryotes, genetic recombination involves the pairing of homologous chromosomes. This may be followed by information exchange between the chromosomes. The information exchange may occur without physical exchange (a section of genetic material is copied from one chromosome to another, without the donating chromosome being changed)(see SDSA pathway in Figure); or by the breaking and rejoining of DNAstrands, which forms new molecules of DNA (see DHJ pathway in Figure). Recombination may also occur during mitosis in eukaryotes where it ordinarily involves the two sister chromosomes formed after chromosomal replication. In this case, new combinations of alleles are not produced since the sister chromosomes are usually identical. In meiosis and mitosis, recombination occurs between similar molecules (homologs) of DNA. In meiosis, non-sister homologous chromosomes pair with each other so that recombination characteristically occurs between non-sister homologues. In both meiotic and mitotic cells, recombination between homologous chromosomes is a common mechanism used in DNA repair.Genetic recombination and recombinational DNA repair also occurs in bacteria and archaea.Recombination can be artificially induced in laboratory (in vitro) settings, producing recombinant DNA for purposes including vaccinedevelopment.V(D)J recombination in organisms with an adaptive immune system is a type of site-specific genetic recombination that helps immune cells rapidly diversify to recognize and adapt to new pathogens.


What is an antiarrestin?

An antiarrestin is an antibody which generates an immune response to arrestin.


Small piece of a pathogen that generates an immune response?

antigen


Which cells exhibit clonal diversity?

Human cells that exhibit clonal diversity are the T and B lymphocytes which are important cells of the immune response.


What is ADA Deficiency?

It is a genetic disease that can disrupt the usual development and activity of your immune system.


What is the process of genetic screening?

Values of Enzymes entered to the immune system, controlling the factor of digestion.


What is a genetic disorder caused by gene?

There are so many genetic disorder caused by sex linked to name few; Auto Immune disorder, Hemophilia, Night Blindness etc.


Immune system recoginize germs and rejects them?

It attacks the virus and recognizes its genetic code so you can't get it again


What are the genetic relationship between the lupus and type 1 diabetes?

genetic relationship between the lupus and type 1 diabetes is important because immune system have in relation with lymphatic system


Why are some people more immune to certain diseases than others?

It is usually down to different genetic make up. A good example is why some people are more immune to HIV and Aids.


During the course of development do cells lose genetic information?

Differential gene expression is not a result of differential loss of the genetic material, DNA, except in the case of the immune system. That is, genetic information is not lost as cells become determined and begin to differentiate.