Impossible to say without a lot more information. It could be worth anywhere from a couple of hundred dollars to several thousand depending on the type of gun (boxlock, sidelock) and condition. Go to www.doublegunshop.com and ask there. British shotguns are very collectable and Hollis is a respected maker.
Isaac Hollis & Sons were English gunmakers from c.1870-1900. They made some very fine guns, and you should have yours evaluated in person by someone familiar with English doubles.
Isaac Hollis & Sons were noted British gunmakers from c.1860-1900. They made many top quality shotguns and rifles with many levels of ornamentation. This is one that should be individually hands-on appraised. sales@countrygunsmith.net
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The second one, Isaac.
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Isaac's father was also named Isaac newton.
Its Isaac.
Sir Isaac Newton.
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Reuel is from Isaac. He was the son of Esau, who was Isaac's son.
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Isaac newton was named after his father Isaac Newton, senior, a farmer.