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since meth causes neurotransmitters to overstimulate they in time down-regulate to compensate for the increased levels of dopamine being released due to the meth but over time they basically start to shut down from working harder than they are meant to and once a neurotransmitter shuts down it can never function again so meth basically kills neurotransmitters over time

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Q: How are neurotransmitters affected by meth?
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