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In a point mutation, one nitrogen base is substituted for the correct base. Since most amino acids can be coded for by more than one codon, there may be no consequence to this mutation. However, sometimes a point mutation results in an incorrect amino acid being added to the amino acid sequence of the protein. This can cause a change in the shape and therefore function of the protein, which can be a harmful mutation. Two genetic disorders caused by a point mutation are cystic fibrosis and sickle cell anemia.
What else can I help you with?
How do you know if a mutation changes the final protein?
You can determine if a mutation changes the final protein by analyzing the DNA sequence to see if the mutation alters the amino acid sequence of the protein it encodes. This can be done through bioinformatics tools or laboratory experiments such as protein expression or functional assays. Additionally, comparing the mutated protein's structure and function to the wild-type protein can also help assess the impact of the mutation.
Will a frameshift mutation always result ina a change in the final protein and why?
Yes, a frameshift mutation will almost always result in a change in the final protein because it disrupts the reading frame of the genetic code, leading to a shift in the sequence of amino acids that are incorporated into the protein. This can have significant effects on the structure and function of the protein.
A researcher made an interesting observation about a protein used to build a cell's plasma membrane The final protein in the plasma membrane was slightly different from the protein made by the ER?
The observed difference between the final plasma membrane protein and the ER protein could be attributed to post-translational modifications. These modifications, such as glycosylation or phosphorylation, can alter the protein's structure and function during its journey through the cell to its final destination in the plasma membrane. This dynamic process allows cells to fine-tune protein function for specific roles in different cellular compartments.
The final three dimentional shape of a protein is?
The final three-dimensional shape of a protein is known as its tertiary structure. This structure is determined by the interactions between amino acid side chains, such as hydrogen bonding, disulfide bonds, hydrophobic interactions, and electrostatic interactions. The tertiary structure is crucial for the protein's function and determines how it interacts with other molecules.
Why does mrna mutation affect the amino acid sequence?
The codon UGU codes for the amino acid Cysteine. The codon UGG codes for the amino acid Tryptophan. Therefore the mutation will cause the amino acid Cysteine to be replaced with Tryptophan. These amino acids are quite different, and the final shape of the protein could be changed as a result. This could affect the function of the protein.
How do you know if a mutation changes the final protein?
You can determine if a mutation changes the final protein by analyzing the DNA sequence to see if the mutation alters the amino acid sequence of the protein it encodes. This can be done through bioinformatics tools or laboratory experiments such as protein expression or functional assays. Additionally, comparing the mutated protein's structure and function to the wild-type protein can also help assess the impact of the mutation.
Will a frameshift mutation always result ina a change in the final protein and why?
Yes, a frameshift mutation will almost always result in a change in the final protein because it disrupts the reading frame of the genetic code, leading to a shift in the sequence of amino acids that are incorporated into the protein. This can have significant effects on the structure and function of the protein.
How does a mutation that alters a codon for a specific amino acid to a different codon for the same amino acid affect protein synthesis?
When a mutation changes a codon for a specific amino acid to a different codon for the same amino acid, it usually does not affect protein synthesis. This is because multiple codons can code for the same amino acid, so the change may not alter the final protein product.
A researcher made an interesting observation about a protein used to build a cell's plasma membrane The final protein in the plasma membrane was slightly different from the protein made by the ER?
The observed difference between the final plasma membrane protein and the ER protein could be attributed to post-translational modifications. These modifications, such as glycosylation or phosphorylation, can alter the protein's structure and function during its journey through the cell to its final destination in the plasma membrane. This dynamic process allows cells to fine-tune protein function for specific roles in different cellular compartments.
After translation what does a protein's function depends upon?
its final three dimensional structure
The final three dimentional shape of a protein is?
The final three-dimensional shape of a protein is known as its tertiary structure. This structure is determined by the interactions between amino acid side chains, such as hydrogen bonding, disulfide bonds, hydrophobic interactions, and electrostatic interactions. The tertiary structure is crucial for the protein's function and determines how it interacts with other molecules.
What affects proetein structure?
Protein structure is dictated by the sequence of amino acids that make up the protein. The charge and polarity of the amino acid side chains decide the final confirmation (or three dimensional shape) of the protein.
What happens to a strand of DNA when there is a change in the base on the other strand?
This is called a "mutation." What ends up happening depends on where the base that changed was located. If the changed base is on the side of the DNA strand that is not used in making mRNA, there will be no difference in the final protein made whatsoever. If the mutation occurs in a part of the DNA that is not coded to make a protein (so called "junk" DNA), there will also be no change in the final protein, because there won't be a protein made. Even if the mutation occurs in a segment of DNA that eventually makes a protein, if the replacement base causes the mRNA to code for an amino acid that is similar to the original base, there will be little change. There is more to it, but that will probably suffice.
Why is a silent mutation called silent?
a mutation that does not affect protein production.
What are the key stages of protein folding and how do they contribute to the overall structure and function of the protein?
Protein folding involves three key stages: primary, secondary, and tertiary structure formation. In the primary stage, amino acids sequence determines the protein's structure. Secondary structure involves folding into alpha helices or beta sheets. Tertiary structure is the final 3D shape, crucial for protein function. Proper folding ensures the protein can perform its specific biological role effectively.
What happens to one strand of DNA when there is a change in a base on a the other strand?
This is called a "mutation." What ends up happening depends on where the base that changed was located. If the changed base is on the side of the DNA strand that is not used in making mRNA, there will be no difference in the final protein made whatsoever. If the mutation occurs in a part of the DNA that is not coded to make a protein (so called "junk" DNA), there will also be no change in the final protein, because there won't be a protein made. Even if the mutation occurs in a segment of DNA that eventually makes a protein, if the replacement base causes the mRNA to code for an amino acid that is similar to the original base, there will be little change. There is more to it, but that will probably suffice.
What happens to one strand of DNA when there is a change in base on the other strand?
This is called a "mutation." What ends up happening depends on where the base that changed was located. If the changed base is on the side of the DNA strand that is not used in making mRNA, there will be no difference in the final protein made whatsoever. If the mutation occurs in a part of the DNA that is not coded to make a protein (so called "junk" DNA), there will also be no change in the final protein, because there won't be a protein made. Even if the mutation occurs in a segment of DNA that eventually makes a protein, if the replacement base causes the mRNA to code for an amino acid that is similar to the original base, there will be little change. There is more to it, but that will probably suffice.
