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An allosteric enzyme is one in which the activity of the enzyme can be controlled by the biniding of a molecule to the "allosteric site". This really just means somewhere other than the active site. Thus allosteric control of an enzyme can be classed in two ways. A positive allosteric modification is the binding of a molecule to the enzyme which increase the rate of reaction. Sort of like catalysing the catalysing effect of an enzyme. Obviously the opposite is true of negative allosteric modification. A good example for this is the activity of phosphofructokinase, which is promoted by a high AMP concentration, and inhibited by a high ATP concentration. This should make sense if you think about the action of a kinase etc.
Wiki User
∙ 14y ago
Wiki User
∙ 11y agoIn feedback inhibition, the allosteric effect lowers the affinity of the enzyme for its substrate.
Wiki User
∙ 10y agoThe active site becomes available to the substrate when regulatory molecules binds to diffirent site of your enzyme or vice versa, you are the controller.
Wiki User
∙ 13y agoan enzyme with more than one subunit
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Which aspect of lac operon regulation is an example of post-translational control?
allosteric regulation of CAP
What mechanism is used to finely tune enzyme activity according to the needs of the cel l?
allosteric regulation
The particular region of an enzyme molecule that combines with the substrate it acts upon is called what?
The area where a molecule other than substrate can attach is called the allosteric site.
What is the general features of allosteric regulation using the feedback inhibition?
enzymes situated at key steps in metabolic pathways are modulated by allosteric effectors these effectors are usually produced elsewhere in the pathway effectors may be feed-forward activators or feedback inhibitors kinetics are sigmoid ("S-shaped")
How allosteric enzymes differ non allosteric?
Allosteric enzymes have the ability to change their conformational ensemble after binding. This changes their affinity at a different ligand binding site.
Some enzymatic regulation is allosteric?
yes
Some enzymatic regulation is allosteric In such cases which of the following would usually be found?
an enzyme with more than one subunit, not feedback inhibition.
What kind of regulation exist for enzymes?
Allosteric regulation and Reversaeble regulation :)
Which aspect of lac operon regulation is an example of post-translational control?
allosteric regulation of CAP
Certain key molecules can regulate biochemical pathways by controlling the rate of enzymatic reactions by binding at?
allosteric sites
What is Role of allosteric enzyme in regulation of purine synthesis?
if the purine synthesis is excess then extra product will bind to the allosteric site then feed back inhibition occurs
True or False 'A change in the primary sequence of a protein can affect allosteric regulation'?
true
Draw a diagram to show how allosteric regulation can be used to regulate biochemical pathways?
A diagram cannot be drawn to answer this question. An answer to how allosteric regulation can be used to regulate biochemical pathways needs to be written or spoken. This question cannot be answered in its current form.
How do allosteric regulation and competitive inhibition compare?
A competitive inhibition and allosteric regulation both involves an inhibitor molecule binding to the enzyme at a different area. The difference between the two is that allosteric inhibitors are modulator molecules which bind somewhere besides the catalytic activity.
What mechanism is used to finely tune enzyme activity according to the needs of the cell?
allosteric regulation
What mechanism is used to finely tune enzyme activity according to the needs of the cel l?
allosteric regulation
Does Allosteric regulation depends on inhibitors binding to the active site of enzymes?
Of course. That is the meaning of ' noncompetitive inhibitor. ' It does not compete with the substrate at the active site but inhibits enzyme activity at the allosteric ( other site ) site.
