Niacin deficiency can be treated effectively with replacement of niacin in the diet. In the case of Hartnup disease, large quantities of niacin may be required for effective reversal of symptoms.
It is due to the deficiency of Vitamin B3 (Niacin)
A niacin or vitamin b3 deficiency.
Niacin deficiency produces pellagra characterized by diarrhea, skin rashes, brain dysfunction, tongue, mouth and vaginal irritation, and trouble swallowing.
Joseph Goldberger believed that pellagra was caused by a nutritional deficiency, particularly a lack of niacin in the diet. He conducted studies showing that pellagra could be prevented and treated by adding foods rich in niacin, such as meat and milk, to the diet.
"Symptoms of mild deficiency include indigestion, fatigue, canker sores, vomiting, and depression. Severe deficiency can cause a condition known as pellagra. Pellagra is characterized by cracked, scaly skin, dementia, and diarrhea. It is generally treated with a nutritionally balanced diet and niacin supplements. Niacin deficiency also results in burning in the mouth and a swollen, bright red tongue."
Niacin, or vitamin B3 occurs in most grains, especially whole grains. Severe deficiency of niacin (which is usually associated with malnutrition, or starvation) causes the disease pellagra. The main symptoms of untreated pellagra are the "4 D's": Diahrrea, dermatitis (red sores or itching), dementia and death. In previous generations, niacin was sometimes called Vitamin PP (for Prevents Pellagra.) The body can create niacin from tryptophan, an amino acid that occurs in milk and meat. People who eat little protein have an increased need for niacin. Many people believe that a mild niacin deficiency slows the metabolism and decreases tolerance to cold. The daily requirement for niacin ranges from 12mg in children to 18 mg in pregnant and nursing women. Niacin defiencies tend to occur only in areas where people eat corn (or maize) instead of wheat, rye or other grains. That's because corn contains niacin in a form the body cannot use. When corn meal or flour is processed with lime, it releases the niacin. One way to prevent a niacin deficiency is to take a daily multi-vitamin and eat a balanced diet including whole grains and poultry, milk, meat, and eggs.
Pellagra
Not being able to perform their best
The answer is folate.
Vitamin A deficiency can be prevented or treated by taking vitamin supplements or by getting injections of the vitamin.
In a terse manner, Niacin (B3) is used in the human body to form coenzymes NAD and NADP - two very important components that are involved in energy production. Pellagra is the main deficiency of Niacin.
Pellagra is a Vitamin B3 (Niacin) deficiency disease. It is caused by severe and prolonged deficiency of Vitamin B3. Symptoms are bilateral dermatitis, dementia, and diarrhea. A prolonged and severe niacin deficiency may cause depression and neurasthenia (weakening of muscles).A deficiency in Vitamin B3 can cause depression, memory loss, canker sores and fatigue.