How can you paint over wood paneling in a room if you can't remove it?

Go to your local hardware store and ask for kilz paint this is a sealent and will allow the new paint to be applied without the wood showing through if you are concerned about grooves i know this sounds wierd but use bondo in the grooves then sand then paint with kilz and then your favorite paint

Answer

a good primer sealer is also just as affective and probably less expencive than kilz ,,personally what I've done is a good latex flat thick in body roll it on covers real good one brand in which I'm talking about is Benjamin moores paint used to be called "vol -pro"real thick in body covers well this product will sometimes cover ram gyproc on one coat expecially if it's an of white color.