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well the dna molecule model was compared to Franklins
Uracil in Watson-Crick base-pairing though non-standard pairs exist.
James Watson and Francis Crick are credited with the base pairing rules and DNA structure in general. Erwin Chargaff is credited with the rules of base pairs in that the number of pyrimidines is equal to the number of purines.
Chargaff discovered that in DNA the percentages of adenine and thymine were the same, and the percentages of cytosine and guanine are the same. This led to the idea of base-pairing between adenine and thymine, and cytosine and guanine.
Sir James Watson and Sir Francis Crick first described the molecular structure of DNA correctly. They not only mentioned the fact that DNA is a helical structure, but also described how the constituting molecules are arranged in the helix. The base-pairing, sugar-phosphate backbone were first described by Watson and Crick.
well the dna molecule model was compared to Franklins
A is always with T and C is always with G
James Watson and Francis Crick are credited with the base pairing rules and DNA structure in general. Erwin Chargaff is credited with the rules of base pairs in that the number of pyrimidines is equal to the number of purines.
Uracil in Watson-Crick base-pairing though non-standard pairs exist.
James Watson and Francis Crick are credited with the base pairing rules and DNA structure in general. Erwin Chargaff is credited with the rules of base pairs in that the number of pyrimidines is equal to the number of purines.
Watson and Crick. Using cardboard cutouts they recognized the helical shape of DNA and the complimentary base pairing rule. That base A pairs with T and Base C pairs with G. They used information from Rosalind Franklin (who determined the width of DNA and the helical shape) and Chargoff (who discovered the equality rule). The structure of this model developed by Watson and Crick suggested a replication mechanism. Hope this helps!
Chargaff discovered that in DNA the percentages of adenine and thymine were the same, and the percentages of cytosine and guanine are the same. This led to the idea of base-pairing between adenine and thymine, and cytosine and guanine.
watson-base pairing
They are: - Adenine and thymine - Cytosine and guanine
The problem with Watson and Crick's original hypothesis of each base bonding to an identical base is that it violates Chargaff's rules of base pairing. Each new base chain is created instead by complementary bonding (Adenine to Thymine and Guanine to Cytosine).
Watson and Crick came up with the base-pairing rule for nucleic acids using Chargaff's rule that in DNA the percentages of adenine and thymine are equal, and the percentages of guanine and cytosine are equal. Refer to the related link below.
In a regular watson-crick double helix base pairing DNA, guanine always pairs opposite cytosine. However this rule holds good only for double helical DNA, as, it is seen in tRNA that guanine (in the anticodon) pairs with cytosine as well as uracil of the corresponding codon in mRNA.