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Q: How did Watson and Crick determine base pairing?
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How did Watson and Crick's model of the DNA molecule explain base pairing?

well the dna molecule model was compared to Franklins


What is an example of the base pairing rule within Watson crick double helix model of DNA?

A is always with T and C is always with G


What scientist are credited with base pairing rules?

James Watson and Francis Crick are credited with the base pairing rules and DNA structure in general. Erwin Chargaff is credited with the rules of base pairs in that the number of pyrimidines is equal to the number of purines.


When two strands of DNA line up a adenine always pairs up with?

Uracil in Watson-Crick base-pairing though non-standard pairs exist.


Who hypothesized that nitrogen bases in DNA occur in pairs?

James Watson and Francis Crick are credited with the base pairing rules and DNA structure in general. Erwin Chargaff is credited with the rules of base pairs in that the number of pyrimidines is equal to the number of purines.


Who made a working model of the DNA molecule?

Watson and Crick. Using cardboard cutouts they recognized the helical shape of DNA and the complimentary base pairing rule. That base A pairs with T and Base C pairs with G. They used information from Rosalind Franklin (who determined the width of DNA and the helical shape) and Chargoff (who discovered the equality rule). The structure of this model developed by Watson and Crick suggested a replication mechanism. Hope this helps!


Explain how chargaff's helped watson and crick model dna?

Chargaff discovered that in DNA the percentages of adenine and thymine were the same, and the percentages of cytosine and guanine are the same. This led to the idea of base-pairing between adenine and thymine, and cytosine and guanine.


What is the rule to join the free nucleotides to the exposed bases of the DNA?

watson-base pairing


What are the two pairs of stable Watson-Crick complementary DNA base pair?

They are: - Adenine and thymine - Cytosine and guanine


What was wrong with watsons hypothesis that gene replication could be acheived if each base in the newly synthesized chain hydrogen hydrogen bonded to an identical base?

The problem with Watson and Crick's original hypothesis of each base bonding to an identical base is that it violates Chargaff's rules of base pairing. Each new base chain is created instead by complementary bonding (Adenine to Thymine and Guanine to Cytosine).


Who proposed the base pairing rule?

Watson and Crick came up with the base-pairing rule for nucleic acids using Chargaff's rule that in DNA the percentages of adenine and thymine are equal, and the percentages of guanine and cytosine are equal. Refer to the related link below.


What base is always opposite guanine?

In a regular watson-crick double helix base pairing DNA, guanine always pairs opposite cytosine. However this rule holds good only for double helical DNA, as, it is seen in tRNA that guanine (in the anticodon) pairs with cytosine as well as uracil of the corresponding codon in mRNA.