The three bodies are acetone, acetoacetic acid and beta-hydroxybutyric acid, although beta-hydroxybutyric acid is not technically a ketone but a carboxylic acid.
They're produced from the burning of fat stores in the body and are excreted out of the body through the kidneys into urine
fat in urine
Diabetes
The pH would be lowered due to the production of ketone bodies and excreted in the urine.
The normal value of excretion of ketone bodies in urine is typically less than 0.5 mmol/L. Elevated levels of ketones in urine, known as ketonuria, can indicate a metabolic condition such as diabetes or starvation. Ketoacidosis, a potentially life-threatening condition, can also cause increased levels of ketones in urine.
Urea is the organic chemical in urine, most abundant waste produced from protein metabolism. Chloride is the most abundant inorganic chemical in urine.
When Insulin level is decreased the pathways such as glycolysis, Glucogenolysis, fatty acid synthesis decreases as a result glucagon stimulates gluconeogenesis, fatty acid lysis, acetyl coA is diverted to form ketone bodies , ketogenic amino acids stored as proteins will form ketones by this ketone bodies increases in blood .. this happens even in high starvation, in DM also.
fatty acids
fatty acids
Diabetes
The pH would be lowered due to the production of ketone bodies and excreted in the urine.
Condition known as Ketosis
diabetes
Rothera's test is used to detect the presence of ketone bodies in a solution (eg urine). it utilizes sodium nitroprusside, liquid ammonia and ammonium sulphate. ammonium sulphate is used to concentrate the ketone bodies to the center of the solution. the other 2 constituents react with ketone bodies to form pink coloured polymerized compound. Rothera's test is used to detect the presence of ketone bodies in a solution (eg urine). it utilizes sodium nitroprusside, liquid ammonia and ammonium sulphate. ammonium sulphate is used to concentrate the ketone bodies to the center of the solution. the other 2 constituents react with ketone bodies to form pink coloured polymerized compound. Ammonium ion is used to precipitate the proteins that may be present.. Because proteins can give a positive result to Rothera's test as well..
Ketonuria is an abnormal condition in which ketone bodies are excreted in the urine. Ketone bodies are partially metabolized fatty acids, which are created when the body is trying to break down stored fats for energy. The liver can only metabolize a certain amount of fat at any given time, with the rate-limiting step being converting ketone bodies into carbohydrates.
Ketonuria means ketones in the urine.Ketonuria is the medical term meaning ketones in the urine.
Proteins-amino acids
The normal value of excretion of ketone bodies in urine is typically less than 0.5 mmol/L. Elevated levels of ketones in urine, known as ketonuria, can indicate a metabolic condition such as diabetes or starvation. Ketoacidosis, a potentially life-threatening condition, can also cause increased levels of ketones in urine.
The Rothera nitroprusside test looks for ketone bodies in urine. It is done by taking 5 mL of urine and adding ten drops of concentrated ammonia water and solid ammonium sulfate. The sample is then analyzed after 15 minutes. If the sample turns purple, then that means there is acetoacetic acid in the urine.