Want this question answered?
Exocytosis. As a result of the influx of Calcium ions, the synaptic vesicles transport the neurotransmitter Ach (Acetylcholine) to the presynaptic membrane, the vesicles fuse to the membrane, and the neurotransmiffer, Ach, diffuses. Once the neurotransmitters cross the synaptic cleft, they bind to the receptors on the post synaptic membrane. Hope it helps a bit.
The cause of synaptic delay is attributed mainly to the time needed for the synaptic vesicles to release neurotransmitter into the synaptic cleft. While it can be considered a combination of binding to the presynaptic membrane (which is relatively a transient process) and subsequent exocytosis of the neurotransmitter, the main factor is release. Additionally, it does take a very short period of time for the neurotransmitter to diffuse across the synaptic cleft and bind to to its receptors on the post-synaptic membrane.
When the action potential (electrochemical signal) reaches the end of the nerve, calcium channels open, causing synaptic vesicles containing neurotransmitters to bind with the neuronal membrane. When this happens, the neurotransmitters are released into the synaptic cleft (process is called exocytosis). Once in the synaptic cleft, they can bind with postsynaptic neuron or muscle cell receptors.
By a chemical released by an axon.
This area is referred to as the synaptic cleft. This area is bound by the end of one neuron (the terminal bouton) and the post-synaptic membrane of the next neuron. When an action potential reaches the terminal bouton, Ca2+ influx triggers the release of neurotransmitters across the cleft, which bind to receptors on the post-synaptic membrane, allowing for an post-synaptic excitatory potential (PSEP) to be formed in the next neuron.
Calcium triggers synaptic vesicles to discharge the neurotransmitter into the synaptic cleft.
Exocytosis. As a result of the influx of Calcium ions, the synaptic vesicles transport the neurotransmitter Ach (Acetylcholine) to the presynaptic membrane, the vesicles fuse to the membrane, and the neurotransmiffer, Ach, diffuses. Once the neurotransmitters cross the synaptic cleft, they bind to the receptors on the post synaptic membrane. Hope it helps a bit.
Neurotransmitters are released from the nerve terminals by a specialized exocytosis process, synaptic vesicles. These are small nearly uniform capsules that join with the cell membrane to expel their contents. Release is both quantal (set amount) and mediated by calcium.
They don't, the neurotransmitters stay on either side of the synapse. Neurotransmitters are released when the synaptic vesicles fuse with the presynaptic neuron's membrane, so as to release them into the synaptic cleft.
Neurotransmitters are stored in synaptic vesicles within axonal terminals for release into the synaptic cleft.
The cause of synaptic delay is attributed mainly to the time needed for the synaptic vesicles to release neurotransmitter into the synaptic cleft. While it can be considered a combination of binding to the presynaptic membrane (which is relatively a transient process) and subsequent exocytosis of the neurotransmitter, the main factor is release. Additionally, it does take a very short period of time for the neurotransmitter to diffuse across the synaptic cleft and bind to to its receptors on the post-synaptic membrane.
calcium entering the axon terminal
Synaptic vesicles in the neuromuscular junction contain acetylcholine (ACh) which is the neurotransmitter for initiating muscular contractions.
1. Nerve impulse reaches synaptic terminal. 2. Synaptic vesicles move to and merge with the presynaptic cell membrane of the motor neuron. 3. Acetylcholine is released into and diffuses across the synaptic cleft. 4. Acetylcholine binds to receptors on the postsynaptic cell membrane of the muscle fiber.
When the action potential (electrochemical signal) reaches the end of the nerve, calcium channels open, causing synaptic vesicles containing neurotransmitters to bind with the neuronal membrane. When this happens, the neurotransmitters are released into the synaptic cleft (process is called exocytosis). Once in the synaptic cleft, they can bind with postsynaptic neuron or muscle cell receptors.
The synaptic knob contains vesicles filled with neurotransmitters. Therefore, Acetylcholine is the neurotransmitter that stimulates skeletal muscle to contract. It is released into the synaptic clefts between motor neuron axons and motor end plates.
Most neurons have a chemical synapse, which is to say that a substance called a neurotransmitter is released from the first neuron (called pre-synaptic) to the next neuron called (post-synaptic). How is the release triggered? When an action potential reaches the terminus (end of the axon) there are specialized calcium channels that are opened (voltage-gated). The calcium bind so the inner membrane and triggers the release of small membrane bound vesicles which spill out their contents of neurotransmitter into the synaptic cleft. The neurotransmitter binds to specific receptors on the post-synaptic membrane and that causes the action potential to propagate on (or for the neurotransmitter to cause an action like a muscle contraction).