The teacher could not teach her class because there was a lot of noise outside that was a very big disruption.
The hurricane caused a major disruption in offshore drilling. Ionizing radiation can cause the disruption of cells within living organisms.
I had to talk to him about his work.
You use synthetic in a sentence... why do you have to make ME do all the work!?
Describe what is your " work ethic"
I was inpress by your work.
edit your work
The king ordered the naysayer to be punished.Naysayers can cause a lot of disruption.
I work very hard.
It depends how you use it. If you use it after something it can be correct. But being in a sentence by itself isn't correct.
There was flexibility in his work schedule.
i will complete my work
She work erratically.