Half-life is trationally employed for the assessment of the degree of accumulation (R) of drug in the body as follows:
R=1/(1-exp(-K*tau)....(1)
This equation applies for single-compartment model drugs. However, for drugs observing multiple compartmental bevavior, the terminal half-life, t0.5(beta), is used. This will, invariable, results in over or under estimation of the drugs' accumulation ration.
As a matter of fact an effective elimination rate constant should, per necessity, take into consideration the exact distributional characteristics of the drug in question. i.e the rate of drug trasfer from one compartment to the other and vis-a-versa.
The following relationship could be of use in this regard:
ERC = (apha*beta)/(K12+k21), where ERC stands for Effective Elimination Rate Constand...
Enjoy....
1000 years
Radioactive decay is measured as a half life and it varies enormously. REALLY enormously! The shortest half life is for artificial elements where the half life is a few millionths of a second, the longest is hydrogen which has a half life of far longer than the lifetime of the universe! Uranium has a half life of around 4000 million years; geologists use uranium (and other elements) to calculate the age of rocks based on how much of the uranium has decayed.
There's no such thing as a half-life combined. The individual isotopes essentially ignore each other. (This is not quite true... if one of them releases neutrons, they could be absorbed by the other one causing it to break apart... but that's a lot more complicated.)
I think you are supposed to calculate this yourself from your own observations. How about also trying dimium, quartium, and dollarium. There shouldd be interesting differences.
c.half-life
it depends on the drug. the cut, and the form in which it is administered. YOU WILL NOT KNOW WHAT THE HALF LIFE IS UNLESS YOU KNOW HOW MUCH YOU HAVE TAKEN. REFER TO HALF LIFE OF MEDICATION IF YOU KNOW THE DOSE TAKEN. HALF LIVES OF DRUGS DIFFER.
The half-life forms a type of clock used to calculate time passed.
half of her life
1000 years
Usually, drugs with these properties should not be formulated into a sustained release dosage form: - Drugs with a half life shorter than 2 hours - Drugs with a half life longer than 5 hours - Drugs with a short half life but a long duration of action - Drugs which have a poor absorption - Drugs with a narrow therapeutic index - Drugs weighing more than 1g - Drugs with a solubility lower than 0.1mg/mL - Drugs with a very low partition coefficient
the half life forms a type of clock used to calculate time passed
This will depend on what drug. Some drugs have a very short half-life and others stay in your system much longer.
drugs get metabolised (broken down) at different rates. Some drugs are metabolised quickly, therefore have shorter half lives and more frequent dosing to maintain optimal levels. some drugs take longer and need less dosing. Other things can also affect half lives
It is infinite, since mathematical knowledge is not destroyed with the passage of time.
refer physical pharmacy book by martin or cvs subrymanam.
are you on drugs !!
Longer than most drugs in that class. Example, Xanax has a half life of 18 hours. Klonopan has a half life of up to 50+ hours. When you get to half, then the other half takes the same amount of time to reduce that half, so you can see where I'm going.