How do you replace the door handle on a 2000 Mercury Sable - Ford Taurus?

Answer 1

Start with removing the door panel.

Then with the window up, strong flashlight and hopefully small hands, survey the linkage that connects to the backside of the handle. Likely to be small nylon/plastic connector on the rod leading to it. Remove/disconnect it.

And last, there should be 2 nuts holding the latch to the door.

While you're in there, take a look at the window 'regulator' - slides. Check for crud build-up and maybe a light greasing just for good-measure.

See "Related Questions" below for information on removing the door panel.