Fare is misshapen with his back
The lady was very misshapen ,because she wasn't eating write.
The nose of the statue was misshapen because of heavy rain
The misshapen hot air balloon drifted slowly toward the line of trees.
The root word of misshapen is "shape."
Shapely
Misshapen pupils in the eye can be caused by conditions such as iris coloboma, aniridia, or trauma. These conditions can lead to abnormalities in the development or structure of the iris, resulting in irregularly shaped pupils. It is important to consult with an eye care professional for proper diagnosis and management.
Knotty and twisted.
happen, basin, raisin, etc...
Missense mutation
Misshapen, monstrous
The adjective is spelled gnarled (twisted, misshapen).
They are not biological and don't "replicate" in a biological sense. They are misshapen proteins and they cause other proteins to also become misshapen, and thus cells just come apart or die.