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After 10 years (and counting) of being on and off corticosteriods at relatively high doses (the highest was 80mgs in hospital, but it is usually 40 to 20 mgs per day), I have found that the best diet while on this drug is a low carbohydrate diet. It helps with fluid retention and prevents Diabetes. It is a difficult diet to follow - especially with the cravings to eat all the time. But a low carb diet allows you to eat a greater quantity of food than you would trying to follow a low fat diet.
If you tend to gain weight while on steriods, I don't think it is possible to avoid gaining some kind of weight gain while on the drug, especially when taking high doses of prednisone, but you can lessen or slow down the weight gain. Another tip is to force yourself to exercise every day. Even if your condition makes it very difficult - exerting your body every day will help.
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