How does the US environmental agency classify carcinogens?

Answer 1

A carcinogen is an agent that can produce cancer (a malignant growth or tumor that spreads throughout the body, destroying tissue). The EPA (Environmental Protection Agency) classifies chemical and physical substances according to their toxicity to humans.

EPA classification system for carcinogens

Group A. Humans Carcinogens

This classification indicates that there is sufficient evidence from epidemiological studies to support a cause and effect relationship between the substance and cancer.

Group B. Probable Human Carcinogen

B: Substances are classified as B carcinogens on the basis of sufficient evidence from animal studies, and limited evidence from epidemiological studies.

B: Substances are classified as B carcinogens on the basis of sufficient evidence from animal studies, with inadequate or nonexistent epidemiological data.

Group C. Possible Human Carcinogen

For this classification, there is limited evidence of carcinogenicity from animal studies and no epidemiological data.

Group D. Not Classifiable As To Human Carcinogenicity

The data from human epidemiological and animal studies are inadequate or completely lacking, so no assessment as to the substance's cancer-causing hazard is possible.

Group E. Evidence Of Noncarcinogenicity For Humans

Substances in this category have tested negative in at least two adequate (as defined by the EPA) animal cancer tests in different species and in adequate epidemiological and animal studies. Classification in group E is based on available evidence; substances Amy prove to be carcinogenic under certain conditions.