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The term 'Metastasis' refers to the process in which the cancer, (malignant tumour), spreads from its original site and establishes additional tumour(s) in different areas in the body. That process can also happen for Breast cancer.

A recent research by the Cardiff University (UK) has identified a gene, named Bcl3, which could be responsible for metastasis in breast cancer. (Genes are specific areas of the DNA where nucleotides (the building blocks of DNA) are joined in a specific order. These areas are holding the blue-print of the traits or characteristics of all organisms, and they are inherited by the off-springs of that organism).

By inactivating (suppressing) the gene Bcl3, the researchers were able to reduce breast cancer metastasis by over 80%! The drug that they developed for the silencing totally stopped the spread in mice. Clinical studies are planned to follow with the drug.

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10y ago

Metastatic breast cancer occurs when the cancer cells within the breasts spread to different organs within the body. This includes the liver, brain, lymph nodes, lungs and bones. 90% of all deaths due to breast cancer are attributed to metastatic breast cancer.

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