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like NADP+ in photosynythesis, each NAD+ accepts a pair of high-energy electrons. This molecule, known as NADH, holds the electrons until they can be transferred to other molecules. By doing this, NAD+ helps to pass energy from glucose to other pathways in the cell.

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What substances are involved in glycolysis and what is the end product of this metabolic pathway?

In glycolysis, glucose is broken down into two molecules of pyruvate. The substances involved in glycolysis include glucose, ATP, NAD, and ADP. The end product of glycolysis is two molecules of pyruvate, along with a net gain of two ATP molecules and two NADH molecules.


Is NAD oxidized or reduced during glycolysis?

NAD is reduced to NADH during glycolysis.


The energy carrier NAD is reduced to what substance?

NAD is an energy carrier which is involved in the process of glycolysis. It is reduced to NADH when a hydrogen atom is added.


What is the difference between NAD and NADH?

NAD (nicotinamide adenine dinucleotide) is a coenzyme that can accept or donate electrons during cellular respiration. NADH is the reduced form of NAD, meaning it has gained electrons. NADH is a high-energy molecule that carries electrons to the electron transport chain for ATP production.


What molecule does fermentation provide to glycolysis?

Pyruvic acid is made during glycolysis and is later used in fermentation.


What molecule is regenerated for glycolysis during fermentation?

NAD+ is the molecule that is regenerated for glycolysis during fermentation. NAD+ is essential for glycolysis to continue in the absence of oxygen by accepting electrons from glucose breakdown.


What is an important example of an electron acceptor that functions in glycolysis?

NAD+ (nicotinamide adenine dinucleotide) is an important electron acceptor in glycolysis. It accepts electrons during the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate, which is a crucial step in the production of ATP.


What happens when no NAD plus is present during glycolysis?

Without NAD+ in glycolysis, the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate cannot occur, halting the production of ATP. As a result, glycolysis is inhibited, and the cell's ability to generate energy through this pathway is compromised.


Can high levels of NADH and low levels of NAD plus stimulate glycolysis?

No it cannot. NADH inhibits glycolysis, the Krebs Cycle and the electron transport chain. HIGH levels of NAD however does stimulate glycolysis but High levels of NADH and low levels of NAD does not stimulate glycolysis but rather inhibits it.


During glycolysis NAD is converted to what?

This is the Glycolysis pathway Glycolysis (the breakdown of glucose to pyruvate and lactate, occurs in the cell cytoplasm): Glucose + 2 ATP + 4 ADP + 2 NAD -> 2 Pyruvate + 2 ADP + 4 ATP + 2 NADH + energy. Oxidation of glucose is known as glycolysis. Glucose is oxidized to either lactate or pyruvate. Under aerobic conditions, the dominant product in most tissues is pyruvate and the pathway is known as aerobic glycolysis. When oxygen is depleted, as for instance during prolonged vigorous exercise, the dominant glycolytic product in many tissues is lactate and the process is known as anaerobic glycolysis. "These studies demonstrate that orderly glycolysis in the erythrocyte is regulated by the NAD-to-NADH ratio and also provide a method that makes possible the in vitro study of erythrocyte glycolysis." The conversion of pyruvate to lactate, under anaerobic conditions, provides the cell with a mechanism for the oxidation of NADH (produced during the G3PDH reaction) to NAD which occurs during the LDH catalyzed reaction. This reduction is required since NAD is a necessary substrate for G3PDH, without which glycolysis will cease. Normally, during aerobic glycolysis the electrons of cytoplasmic NADH are transferred to mitochondrial carriers of the oxidative phosphorylation pathway generating a continuous pool of cytoplasmic NAD NADH


Why can't lactate be converted to NAD?

Lactate cannot be directly converted to NAD because lactate is a product of anaerobic glycolysis, where NAD+ is reduced to NADH during the conversion of pyruvate to lactate. The regeneration of NAD+ from NADH occurs primarily in aerobic conditions through the electron transport chain. In anaerobic conditions, lactate accumulation allows glycolysis to continue by recycling NADH back to NAD+, but it does not convert lactate itself into NAD. Thus, lactate serves as a temporary storage form of reducing equivalents, rather than a source for NAD regeneration.


What compound must be generated during lactic acid fermentation for glycolysis to continue?

During lactic acid fermentation, NAD+ must be regenerated for glycolysis to continue. In the absence of oxygen, NADH produced in glycolysis is converted back to NAD+ when pyruvate is reduced to lactic acid. This regeneration of NAD+ allows glycolysis to persist, enabling the production of ATP in anaerobic conditions.