It depends on where you are going in Louisville. From Frankfort to the east side of Louisville the drive is 35-40 minutes.
It will take about 11 hours to drive the 726 miles. (1,168km).
According to MapQuest and depending on where you start out in Louisville and go to in Birmingham, it will take at least 5 hours and 35 minutes to drive.
Almost 14 hours.
5 hours
21/2 hours
According to mapquest.com, it will take approx. 16 1/2 hours to drive the 1083.76 miles from Miami Florida to Louisville Kentucky.
The distance between Salem and Florence is approx. 130 miles and about a 2.5 hour drive.
34 hours
46 minutes
Chigago IL to Louisville, KY, USA 297 mi - about 4 hours 47 mins
It is 106.67 miles according to MapQuest.