The distance between Missouri, USA, and Detroit, MI, is 660 miles and will take about 10 Hours 20 Minutes of driving time.
A long time.
That would depend on where in Florida and where in Missouri you are.
Mapquest
12 hrs
Shams Rule
2536 kilometers
4 hours
From where?!?
It will take about 4 to 4 1/2 hours to drive from Detroit to Traverse City.
It take 9 hrs and 51 mins from Waco, Texas to Richland, Missouri
it takes about 1 week
4-5 hrs