Well you can't drive on a aeroplane for a start
5hrs 32 minutes
South Carolina and Georgia.
It would be a 185 mile drive, but they are about 167 miles apart.
The Jacksonville Landing is located on 2 Independent Drive #250, in Florida, USA. It is located in the northeastern most part of the state, bordering along Georgia.
About 4 hrs
The distance between Macon Georgia and Jacksonville Florida is 271.3 miles. This would take approximately 3 hours and 55 minutes to drive by car.
1 EverBank Field Drive Jacksonville, Florida 32202
Mapquest
About 3.25 hours.
The fastest route to drive from Orlando Florida to Jacksonville Florida is on a US Interstate highway. In this case that highway is Rt. 95.
Orlando, Florida to Jacksonville, Florida is 2 h 7 min (141.2 mi) via I-4 E and I-95 N