Sickle cell trait is an inherited blood disorder that affects 1 million to 3 million Americans and 8 to 10 percent of African Americans. Sickle cell trait can also affect Hispanics, South Asians, Caucasians from southern Europe, and people from Middle Eastern countries.
A very high ratio of 1 in 11.
Sickle cell trait is an inherited blood disorder that affects 1 million to 3 million Americans and 8 to 10 percent of African Americans. Sickle cell trait can also affect Hispanics, South Asians, Caucasians from southern Europe, and people from Middle Eastern countries.
A very high ratio of 1 in 11.
A very high ratio of 1 in 11.
A very high ratio of 1 in 11.
A very high ratio of 1 in 11.
Balanced Selection
Not all African American babies have sickle cell anemia. It must be inherited for an African American (usually male) to develop the condition.
A very high ratio of 1 in 11.
The sickle cell allele can be maintained in the central African population, above the frequency of gene mutation (balancing selection), because the heterozygous sickle cell individuals have an advantage in lifespan, in this malaria stricken region, over the homozygous alternatives. Homozygous sickle-sickle individuals die early from the sickle cell disease. Homozygous nonsickle-nonsickle die early from malaria. The heterozygous sickle-nonsickle have a higher survival against malaria and therefore the sickle cell allele is balanced selected.
codominant
codominant
NO
The pro of sickle cell hemoglobin is that if you have only one allele for sickle cell hemoglobin and the other allele is normal, then you are immune to malaria.