About 8h10 with one change (at Dresden, Nürnberg, or Regensburg).
The journey can also be done in about 6 hours by travelling to Nürnberg by train (journey time: 2h08) and from there taking an express bus (reservation required) to Prague (journey time: 3h37).
Seven and a half hours.
I have taken the train from Frankfurt to Berlin and it takes around 2.5 hours.
At an average speed of 40 miles per hour it would take 6 hrs and 30 minutes to get to Prague from Frankfurt. If you were lucky enough to average 55 miles per hour it would take around 4hrs and 45 minutes.
7 hours
3 hours by car.
10 hours
approximately 5.5 to 6 hours depending on how many times one has to change train either at Basel or Bienne.
It isn't. Frankfurt is one hour ahead of London.
2 hours and 55 minutes.
between 21 and 22 hours
10 hours
2 hours