If you are referring to Detroit, Michigan and Gatlinburg, Tennesse, they are approximately 679 miles away from one another.
It is 379 miles between Indianapolis, IN and Gatlinburg, IN.
326 miles
535 miles
201 miles
about 485 miles
111 miles
379 miles
50miles
Mapquest says about 554 miles (about 9 hours driving time).
655 miles
about 200 miles
240 miles