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How much protein is in bacteria?


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January 29, 2008 1:40PM

There is approximately 100-155 fg/cell of protein and ~20 fg/cell of RNA based on Cox, R.A. (2004) Quantitative relationships for specific growth ratios and macromolecular compositions of Mycobacterium tuberculosis, Streptomyces coelicolor A3(2) and Escherichia coli B/r: an integrative theoretical approach. Microbiology. 150:1413-26.

As a side, there is also ~4.2 fg/cell of DNA based on Kubitschek, HE and Friedman, MC (1971) Chromosome replication and the division cycle of Escherichia coli B/r. Journal of Bacteriology. 107:95-99.