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Since erythropoietin is synthesized in the kidney, the effect of kidney failure is to depress red blood cell production. Thus, anemia occurs. The average hemoglobin level for an individual suffering from ESRD (end stage renal disease) is no more than 10.8 in the vast majority of cases.

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Q: How would kidney failure affect rbc production?
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The kidneys filter waste products from the blood, so if they don't work properly, you are essentially poisoned by your own cell waste. Kidney failure results in death if you don't get a transplant or undergo kidney dialysis frequently.


Why would damaged kidneys affect health?

The kidneys filter waste products from the blood, so if they don't work properly, you are essentially poisoned by your own cell waste. Kidney failure results in death if you don't get a transplant or undergo kidney dialysis frequently.


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