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There is not really enough information in the question to answer it properly. You would need to know what trait the D and d stood for to give a proper answer.

If the dog's genotype is Dd and it has the disease, this suggests that the disease is caused by a dominant allele. A healthy bitch would have the genotype dd and half of her pups would have the disease. There is no mate which would produce all heathly pups.

If the dog is symptom free then the disease is caused by a recessive allele. In which case the dog should be matted with a dog with the genotype DD to have 100% symptom free pups. Mating Dd to Dd would give 75% symptom free pups and 25% sufferers. Mating the Dd dog to a dd dog would give 50% disease free pups and 50% sufferers.

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Q: If a dog's genotype is Dd if it has a disease what genotype does another mate have to have in order for have of the puppies to not have a disease?
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