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If a woman had a distant relative or an ancestor with Down syndrome would it increase the chances that this woman would bear a child with Down syndrome?
Wiki User
∙ 16y ago
I would say no. Down syndrome is caused by an extra chromosome (extra pair of chromosome 21). If anyone has three chromosomes 21, they have Down; you can't have "latent Down" and transmit it to your children.
What increases the risk for Down most is older parental age, especially maternal (>35, and especially >40). Most standard prenatal screenings now can detect Down in the fetus very early on.
Wiki User
∙ 16y ago
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