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When enzymes are heated above an optimum temperature of 37.7oC, they become denatured. This means their active site (the region where substrates are broken down or built up) loses its shape. Structurally, the enzyme molecule is deformed. In terms of function, the substrate becomes unable to fit into the active site, so no reaction can take place, therefore metabolic rate falls. This can be fatal if the fever is high enough, so as to denature all enzymes, which would render them permanently useless.

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Q: If an enzyme was heated as when an person has a high fever what happens to its structure and also its function?
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Related questions

What happens to an enzyme when it is heated?

When an enzyme is heated it is denatured, which means that it can no longer function.


Why does an enzyme become denatured when heated?

Heat breaks chemical bonds in protein molecule which distorts its structure and catalytic activity .


Why does pH denature enzymes?

If the temperature is increased then the enzyme becomes denatured. This happens at about 50-60 degrees in the human body. When enzymes are heated up too much they vibrate so vigorously that the bonds holding the protein structure in its specific shape break. The enzyme shape changes and the substrate no longer fits in to the active site. An enzyme which has become denatured is permanently inactive and will take no further part in reactions.


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when an enzyme is exposed to conditions it is not made for, it will denature and loose its shape. THEY DONT DIE THOUGH! they cant die because enzymes are never alive, they are just proteins. i know this stuff cause im taking my biology 2 exam in 2 weeks ;)


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