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What type of mutation in the DNA leads to a single change in the amino acid sequence of the protein?
Wiki User
∙ 8y ago
Yes, it already has by changing the amino acid you have a mutation. That one amino acid counld be in the active site of an enzyme and that one amino acid being changed could result in loss of function or reduction in function of the enzyme. Sickle cell animea is caused by a single such amino acid substiution.
Wiki User
∙ 14y ago
Wiki User
∙ 9y agoNot always. Mutations in condons do not change the amino acid sequence.
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What would a single change in the sequence of nitrogenous bases in a DNA molecule most likely result in?
A mutation
What does a DNA molecule look like with a mutation?
A mutation is a change in the sequence of nucleotides that make up DNA. Changes can cause a change in phenotype when they change a gene or regulatory sequence, but can be silent mutations when a stretch of so called 'junk DNA' is affected. A mutation can be either a spontaneous occurrence or induced by environmental factors such as free radicals / ionising radiation. Mutation is considered to be the driving force behind evolution, regardless of where it all originates from: evolution (change) through mutation is a fact.
What is the type of mutation that causes bloom's syndrome?
This mutation deletes six DNA building blocks (nucleotides) and replaces them with seven others at position 2281. The blmAsh mutation results in the production of an abnormally short, nonfunctional version of the BLM protein. This called a missense mutation.The mutation is recessive and both parents must carry it to produce a child with the disorder. It is found in populations where there are close relatives that marry.Other BLM gene mutations change single protein building blocks (amino acids) in the protein sequence or create a premature stop signal in the instructions for making the protein.
How a change in the sequence of nucleotides in a strand of DNA might cause a protein to malfunction?
The sequence of nucleotides is altered and therefore, the amino acid that is to be added to the peptide chain will be altered. hence the protein will be different. This protein can be functionless (will be degraded). If it turns out to be toxic, then there may be symptoms.
What are the impact of mutations and how mutations can have no impact?
Mutations are usually anomalies in the sequence of a particular strand of DNA. The change is the sequence can be of various kinds and their individual effects vary. Sometimes mutations occur but they are never expressed. In such cases, on the whole, the mutation has had no impact. Changes in a single nucleotide can change the reading frame for protein coding regions and can cause misreading of the genetic code. For example, nonsense mutations caused by the exchange of a nucleotide leading to a stop codon can cause truncation of a protein. On the other hand, we can have silent mutations which show no effect because the nucleotide that has been exchanged does not cause change in amino acid sequence. So this would be an example of a mutation which shows no effect.
What is mutation.?
A mutation is a permanent change in the DNA sequence of a gene. Mutations in a gene's DNA sequence can alter the amino acid sequence of the protein encoded by the gene. How does this happen? Like words in a sentence, the DNA sequence of each gene determines the amino acid sequence for the protein it encodes. The DNA sequence is interpreted in groups of three nucleotide bases, called codons. Each codon specifies a single amino acid in a protein. butthole
What would a single change in the sequence of nitrogenous bases in a DNA molecule most likely result in?
A mutation
What does a DNA molecule look like with a mutation?
A mutation is a change in the sequence of nucleotides that make up DNA. Changes can cause a change in phenotype when they change a gene or regulatory sequence, but can be silent mutations when a stretch of so called 'junk DNA' is affected. A mutation can be either a spontaneous occurrence or induced by environmental factors such as free radicals / ionising radiation. Mutation is considered to be the driving force behind evolution, regardless of where it all originates from: evolution (change) through mutation is a fact.
A change in a single base pair of the DNA molecule that affects the synthesis of an entire protein is called what?
point mutation.
A change in a single base pair of the DNA molecule that affects the synthesis of an entire protein is called...?
a point mutation
What is the type of mutation that causes bloom's syndrome?
This mutation deletes six DNA building blocks (nucleotides) and replaces them with seven others at position 2281. The blmAsh mutation results in the production of an abnormally short, nonfunctional version of the BLM protein. This called a missense mutation.The mutation is recessive and both parents must carry it to produce a child with the disorder. It is found in populations where there are close relatives that marry.Other BLM gene mutations change single protein building blocks (amino acids) in the protein sequence or create a premature stop signal in the instructions for making the protein.
How a change in the sequence of nucleotides in a strand of DNA might cause a protein to malfunction?
The sequence of nucleotides is altered and therefore, the amino acid that is to be added to the peptide chain will be altered. hence the protein will be different. This protein can be functionless (will be degraded). If it turns out to be toxic, then there may be symptoms.
What produces a nonsense mutation?
A nonsense mutation is a genetic mutation in a DNA sequence that leads to the appearance of a stop codon where previously there was a codon specifying an amino acid. DNA is a chain of many smaller molecules called nucleotides. During protein formation, DNA (or RNA) nucleotide sequences are read three nucleotides at a time in units called codons, and each codon corresponds to a specific amino acid or stop codon, which is also called nonsense codon because it does not code for an amino acid and instead signals the end of protein synthesis. Therefore, nonsense mutations occur when a premature nonsense or stop codon is introduced in the DNA sequence. When the mutated sequence is translated into a protein, this premature stop codon results in the production of a shortened, and likely nonfunctional, protein.
Why does a deletion mutation usually cause more defects during protein synthesis than a point mutation?
Deletion mutations can affect the entire base sequence.
Changes in DNA sequence of a single gene are called?
Changes in a DNA sequence of a single gene is called a point mutation. These mutations can be harmful or not to the organism.
A change in a single DNA nucleotide is called?
Yes but Mutation point 😂 A. Point Mutation
A mutation that alters a single amino acid within a protein can alter?
the primary, secondary, and tertiary level of a protein structure because once an amino acid is effected by a mutation in a single amino acid it ruins the entire protein on all levels
