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Do contraceptive pills work if you don't believe in them.. Any evidence from clinical trials with a placebo group. Reason I ask is that clinical trials have proven that placebos work for pain reliev?
Birth control pills are quite reliable. They are made with hormones that do change what happens inside a woman's body, regardless of what she may or may not believe. They do not depend upon the placebo effect.
Why wouldn't a doctor be notified if a patient is getting a placebo or a treatment?
In a double-blind test, if the doctor treating a patient knows whether the patient is getting a real treatment or not, they may (perhaps unconsciously) treat the patient differently, or worse let slip that the patient is taking the placebo. This will affect the results (as it changes the effect of the placebo) and can ruin a drug trial.
What information does the clinicaltrials.gov website provide?
On the website you can find information about clinical trials in numerous countries. As well as mandatory registration requirements for a clinical trial. One may also learn background information on different current clinical trials.
How do you know if you received a placebo medication?
Although it is hard to tell exactly if you are given a placebo or not, here are some ways that may help: Placebo medications usually will not produce side effects. If you are experiencing no side effects while an active medication probably would produce side effects, then you may have received a placebo. If the desired effects are not occurring, then you may have received a placebo.
A subject is given a sugar pill and is told it may treat anxiety This person may experience?
the placebo effect. CHIKA CKIKA YEAH!
Double dummy in blind clinical trials?
Double-Dummy A technique for retaining the blind when administering supplies in a clinical trial, when the two treatments cannot be made identical. Supplies are prepared for Treatment A (active and indistinguishable placebo) and for Treatment B (active and indistinguishable placebo). Subjects then take two sets of treatment; either A (active) and B (placebo), or A (placebo) and B (active). Difficulties in achieving the double-blind ideal can arise: the treatments may be of a completely different nature, for example, surgery and drug therapy; two drugs may have different formulations and, although they could be made indistinguishable by the use of capsules, changing the formulation might also change the pharmacokinetic and/or pharmacodynamic properties and hence require that bioequivalence of the formulations be established; the daily pattern of administration of two treatments may differ. One way of achieving double-blind conditions under these circumstances is to use a 'double-dummy' technique. This technique may sometimes force an administration scheme that is sufficiently unusual to influence adversely the motivation and compliance of the subjects. Ethical difficulties may also interfere with its use when, for example, it entails dummy operative procedures. Nevertheless, extensive efforts should be made to overcome these difficulties.
What is a negative placebo effect like?
The placebo effect can have a negative influence also, a nocebo. If a placebo is given that the patient believes to be harmful to their health in some way, he or she may develop symptoms appropriate to this belief.
What is the meaning of a 'clinical trial overview'?
A clinical trial is a particular type of research that tests one treatment against another. It may involve either patients or people in good health, or both. Small studies produce less reliable results so studies often have to be carried out on a large number of people before the results are considered reliable.
What is a double blind crossover study?
I want to know if a medication has the desired effect. I'm going to give half the subjects the 'live' med, and half will get a placebo. The subjects will not know which one they are getting. That's one level of "blind". Studies show that there is a measurable affect based on the fact that the person distributing the med's knows who is getting the med and who is getting the placebo. So I am going to package the med's and give them to the distributing nurse, and the nurse will not know who is getting the med and who is getting the placebo. That is "double blind" model.
What does glucosamine do for you?
Oral glucosamine is commonly used for the treatment of osteoarthritis. Since glucosamine is a precursor for glycosaminoglycans, and glycosaminoglycans are a major component of joint cartilage, supplemental glucosamine may help to rebuild cartilage and treat arthritis. Its use as a therapy for osteoarthritis appears safe, but there is conflicting evidence as to its effectiveness. A randomized, double-blind, placebo-controlled trial found glucosamine sulfate is no better than placebo in reducing the symptoms or progression of hip osteoarthritis.There are two main types of glucosamine, Glucosamine Sulfate and Glucosamine hydrochloride. In a placebo controlled trials of Knee pain the Glucosamine Hydrochloride failed to show superority over placebo (GAIT) but a similar trial of the Glucoasmine Sulfate showed superiority over placebo and paracetamol in the control of pain.
What is the purpose of clinical research organizations?
An experienced Clinical Research Organizations help you to find a way to determine appropriate dosing of new medications and use of medical devices as well as ensure they are safe and effective. Medications being researched for safety and effectiveness are known as investigational drugs or study drugs. I have searched get connected with some medical research sites these may help you to get more and refined information related to your search. Please find below the websites: hrmdresearch alliancesites accelresearchsites Let me know if this will help you!
What is a placebo used for in scientific studies?
Placebo is a dummy drug, which is identical in appearance to the drug under study but will have no therapeutic property. Placebos are used in clinical trials in order compare the effect of drugs on humans. The placebos are given to the control group and the drug is given to the treatment group. The effects on both the groups are then documented and compared to see the action of the drug in humans. Placebos are used in randomized, controlled trials. Know more about the processes in clinical research: http://www.crocareers.in
