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You should discuss this with your physician. Alprazolam (Xanax) and oxycodone taken together can have significant sedative and respiratory effects. I would avoid taking them together if you have to perform any activities which require you to be awake and alert.

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15y ago
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14y ago

Firstly, it's spelled Xanax. Second, oxymorphone is an EXTREMELY potent opiate and should probably not be mixed. But benzo's and opiates do synergize quite well, so your experience could be quite enjoyable...if the doses are correct!

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10y ago

No you shouldn't take them together it could kill you. The xanax slows your heart rate down and roxicodones speeds your heart up so your brain will over load and send you into cardiac arrest an so u die

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Q: Is it all right to take xanax while on oxycodone?
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