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Is it possible that an Rh negative be compatible to an Rh positive blood in a cross-matching procedure?
Wiki User
∙ 11y ago
If the patient is rh - and the donor blood is rh +, then transfusing them is acceptable in a serious emergency when there is no time to wait for properly cross matched blood, ie there is about a 97% chance it wont kill them.
What will happen is they will develop anti D so if you then try and do the same thing 48 hours or more later it will cause a massive and potentially fatal transfusion reaction, and potentially cause problems with future pregnancies. If they already had anti D present in the first place which is possible due to pregnancy or previous transfusions then they would also have this reaction, about 3% of patients have anti D which is why the above transfusion is approx 97% safe.
If an rh- patient has been transfused rh+ blood and it is detected within a few hours giving them a dose of anti D can prevent them making thier own and avoid the potential for future complications.
Wiki User
∙ 11y ago
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Is it possible that an Rh negative blood be compatible with an Rh positive in a crossmatching procedure?
In crossmatching you don't actually mix the whole blood samples. You will mix the red blood cells of the donor with the plasma of the patient. So if the patient is Rhesus positive, it wont have antibodies in the plasma against the Rhesus factor on the red blood cells of the donor. So a crossmatch with either a negative or positive donor will be allright. So in this case, it is indeed possible.
Is negative blood compatible wiyh positive blood?
Negative blood can be given to someone with positive blood. Positive blood CANNOT be given to someone with negative blood.
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