By plane. If you are driving, I5 would be the quickest, most direct route.
The A1 motorway.
If you fly, it is 334 miles. If you drive, the quickest route is 468 miles.
I-65 SOUTH (from INDIANA).
maps.google.com
The quickest route is 1,958 miles.
The quickest driving route to Eliat from Jerusalem is 308 km
Check Mapquest.com
Approx. 170 miles in a straight line. If you're driving, then Google Maps states that the quickest route is 287 miles.
The shortest and the quickest route is I-85 N.
I-75 to Chattanooga, I-24 to Nashville, I-65 to Gary, IN, and I-90 into Chicago.
It depends on your route, but the approximate driving distance (using major roadways) is 600 miles.