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The HMG-CoA Reductase reaction is rate-limiting for cholesterol synthesis.
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∙ 14y ago
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How does Lipitor work?
It inhibits the rate-limiting enzyme (HMG-CoA reductase) in the multi-step pathway of cholesterol synthesis, in the liver.
What is the slowest chemical reaction?
The slowest of the elementary steps that make up a complex reaction is called the rate limiting step. Sometimes it is also called the rate determining step.
Which of the following enzymes catalyzes the rate-limiting step of glycolysis?
Phosphofructokinase
Which enzyme catalyzes the rate-limiting step of glycolysis?
Phosphofructokinase (PFK)
What stimulates acth?
ACTH stimulates lipoprotein uptake into cortical cells. This increases the bio-availability of cholesterol in the cells of the adrenal cortex.ACTH increases the transport of cholesterol into the mitochondria and activates its hydrolysis.ACTH Stimulates cholesterol side-chain cleavage enzyme, which makes the rate-limiting step in steroidogenesis. This results in the production of pregnenolone.
What does ACTH stimulate?
ACTH stimulates lipoprotein uptake into cortical cells. This increases the bio-availability of cholesterol in the cells of the adrenal cortex.ACTH increases the transport of cholesterol into the mitochondria and activates its hydrolysis.ACTH Stimulates cholesterol side-chain cleavage enzyme, which makes the rate-limiting step in steroidogenesis. This results in the production of pregnenolone.
How does simvastatin work in 70 year old male patient who has post coronary angiography bypass graft with elevated LDL?
Statins are lipid lowering agents specifically a HMG-CoA reductase inhibitor that , inhibits the rate-limiting step in cholesterol biosynthesis by competitively inhibiting HMG-CoA reductase therefore lowering the synthesis of cholesterol in the liver since cholesterol is a major determinant in atherosclerosis.
What is a rate governed process in Chemical Engineering?
A rate-governed or rate-limiting process is a process in which there are several steps; however, the rate of one or more steps is much slower than all the others. The rates of the previous steps and following steps are assuming to be infinite, and the rate of the process only depends on the rate-limiting step(s).
How do statins improve cholesterol?
Statins are medications that lower blood pressure. They are able to block the action of a chemical in the liver that makes cholesterol. By lowering the cholesterol in the body, your blood pressure is lowered.
Why is limiting your cholesterol level good?
because preventing diabetes
What are the rate-limiting enzymes for ATP-PC system?
The rate limiting enzyme reaction is the creatine kinase reaction
A limiting nutrient is to ecosystem productivity as a limiting factor is to population?
growth rate
