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Letrozole (Brand Name: Femara) is an orally active nonsteroidal compound that reversibly inhibits aromatization all over the body, as well as that within the Breast cancer cells, resulting in nearly total estrogen deprivation.It is a selective inhibitor of estrogen formation.it inhibits the estrogen synthesis by inhibition of aromatase enzyme that is crucial for the formation of estrogen.The proliferation of estrogen-dependent breast cancer is suppressed to a greater extent than with tamoxifen.for more information about femara is on DrugsBanksdotcom

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Q: Should you take Evista after 5 years of Tamoxifen and five years of femara?
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How long is tamoxifen taken for?

Usually 5 years


Why are you bleeding after 5 years of taking tamoxifen?

Tamoxifen is an anti-estrogen drug used to prevent the growth of ER+ breast cancer. It is typically used in pre-menopausal women, and while it may cause menopause to start earlier than it would have otherwise, that isn't typical. In most women, the ovaries work normally and their periods will continue as before. In some women who were already close to menopause, menstrual periods will stop. Tamoxifen raises the risk of endometrial and uterine cancer, so if you suddenly start to bleed after years of not bleeding, you should go see your physician and have an exam.


How does tamoxifen work?

Most breast cancers are Estrogen fueled , called receptor positive. After treatment, most women with that type of breast cancer are put on Tamoxifen for 3-5 years , it is an Estrogen blocking drug and can aid in preventing the BC from returning.


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