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because it defects the lung, and trust me I got a A star for science so I know
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What are the advantages of thalidomide?
the benifits of thalidomide are;high doses caused limb defects in the offspring of rabbits, but not other animals.it causes defects in humans by interfering with the growth and development of new blood vessels.
What teratogen causes severe limb deficiencies?
Thalidomide.
When in pregnancy did thalidomide affect baby?
The thalidomide sensitive period goes from day 21 past conception onwards to day 42. (Dr Janet McCredie, "Thalidomide - Birth Defects Explained", London, The Royal Society of Medicine Press, 2007, p. 189 and many other places in the book} McCredie suggests, p. 126, that the hypothesis of neural crest injury is the underlying pathogenetic mechanism of many congenital malformations. And concludes, pp. 150 - 151, that the thalidomide-sensitive period coincides with neural crest development, but not with limb development That's what I understand. I have no knowledge of (human) biology and related sciences. I'm only a dumb thalidomide-monster.
What side effects are there for thalidomide?
Thalidomide was originally given to pregnant women who suffered from morning sickness, it is not also used to treat leprosy. Although it often cured women's morning sickness, it actually causes severe limb dis-configurements in newborn children.
What is thalidomide?
Thalidomide is a drug that was prescribed to pregnant women in the 60's ish to relieve the symptoms of morning sickness that was later discovered to cause birth deformities (particularly malformed limbs). -a sedative and hypnotic drug; withdrawn from sale after discovered to cause severe birth defects because it inhibits angiogenesis -Thalidomide is a sedative-hypnotic, and multiple myeloma medication. The drug is a potent teratogen in rabbits and primates including humans -A drug that was sold during the late 1950s and 1960s as a sleeping aid, and to pregnant women as an antiemetic to combat morning sickness and ... -tranquilizing drug that can have a teratogenic effect on the auditory system of the developing embryo when taken by the mother during pregnancy ... -A drug being investigated for its potential as an angiogenesis inhibitor. -An emblematic example of a chemical applied to health. Its use in treating sickness during pregnancy in the 1960s resulted in birth defects. The birth defects were caused because thalidomide changes the growth and development of new blood vessels (angiogenesis) in the developing babies. ... -A drug rarely used because of its disastrous side effects in pregnancy, but proving useful in some lupus with severe skin lupus. -A drug to help morning sickness that was withdrawn in 1961 after it was found to cause limb deformities in babies born to women who had taken it -drug which is a powerful human teratogen. First synthesized in Germany in 1954 as a new antihistamine, the drug was found to be a safe.
Why is thalidomide still available today?
THE FIRST CONTRIBUTOR ARGUED: Thalidomide has legitimate medical uses. For example, it can be used to treat [Hansen]'s disease (used to be called leprosy) and multiple myeloma. The risk vs reward ratio for all drugs must be carefully evaluated. The risk for pregnant women taking thalidomide for morning sickness clearly outweighs any possible benefit that the woman might receive through the mitigation of her morning sickness. So those women taking thalidomide for other treatment must take every precaution against becoming pregnant. But this is no different than other drugs that are demonstrated teratogens, such as Acutane, which is prescribed for the control of serious acne THIS CONTRIBUTOR CALLS HIMSELF THE SECOND CONTRIBUTOR AND REPLIES: Every mother knows that her child should not play with a toy the child does not understand. The mechanism of the biological action of thalidomide is still being debated. Human nature is constituted as such that some individuals who have inside knowledge about the effects of thalidomide will 'always' deliberately and unnoticeably cause the serious harm thalidomide can 'so easily' cause. They do that precisely because the damage is so serious to the mother and to the child and because they can do that so easily and without being noticed. It may be that 'in clinical trials', thalidomide is shown to be effective against many things. But 'in real life', it is given to unsuspecting girls. TWO REMAINING PUZZLES (for the second contributor): ONE Thalidomide is a cure against Hansen's disease, leprosy. The second contributor is no medical doctor, but his understanding of leprosy is that it "takes" limbs "away". (1) The effect of thalidomide on foetuses is thus similar to the symptoms of leprosy on human beings. Still, thalidomide is cure of/against leprosy. Since Aristotle, the principle of non-contradiction (the PNC) says that it is impossible to be and not to be at the same time and in the same respect. Contrary to what many authors argue, this principle, or law, is not applicable to reality, only to thought. (2) Thought is submitted to the PNC. Reality is not. How can the thought of the advocates of the use of thalidomide get away with the apparent contradiction that thalidomide is both the cause of and the cure of leprosy(-like symptoms)? Is it being argued that using thalidomide on pregnant women and using it on non-pregnant people suffering of leprosy is using it in a different respect? Multiple myeloma, say the ophthalmologists? TWO Thalidomide attacked the embryo, not the infant. It attacked the sensory, not the motor "nerves". (3) It thus did not act on the limb bud. Indeed, thalidomide caused upper limb deformities by action before the limb had existed. (4) The damaging drug may have been developed by the Nazis as an antidote to "nerve" gas. (5) Again, the second contributor is no medical doctor, but he's surprised by the double occurrence of the same noun "nerve". THE ULTIMATE PUZZLE: Why is thalidomide still available today? NOTES (1) Left untreated, leprosy can be progressive, causing permanent damage to the skin, nerves, limbs and eyes. Leprosy does not directly cause body parts to fall off on their own accord; instead they become disfigured or autoamputated as a result of disease symptoms. http://en.wikipedia.org/wiki/Leprosy (2) Fernand Van Steenberghen, (F.-X. de Guibert, ed.), Philosophie fondamentale , Longueuil, Québec, Editions du Préambule, 1989, footnote p. 296: Contrairement à ce qu'affirment beaucoup d'auteurs, ces principes [the principle of non-contradiction, the law of the excluded-middle and the law of identity] sont des Lois logiques ou des Lois de pensée comme telle et non des Lois de l'ordre réel. (3) Janet McCredie, "Beyond Thalidomide - Birth Defects Explained", London, The Royal Society of Medicine Press, 2007, p. 405 (4) McCredie, p. 152 (5) From The Sunday Times February 8, 2009 Thalidomide 'was created by the Nazis' The damaging drug may have been developed as an antidote to nerve gas Daniel Foggo http://www.timesonline.co.UK/tol/life_and_style/health/article5683577.ece
If a birth defect were said to be cause by a teratogen it was caused by what?
Thalidomide, used for nausea, is a potent teratogen. It stops the growth of limb buds in developing embryos and other fetal anomalies if the mother takes the drug during the first trimester. See the link for a list of anomalies that can be expected.
Does fish have limb?
No, fish have fins, not arms and legs, I thought they did but I was wrong
What did Victorians say instead of leg because they thought it was rude?
Limb
How do trematodes harm frogs?
They cause limb malformations.
What is rhymes spin?
I Thought of these: dim chin win thin limb sin
Leg was thought to be rude in Victorian times what word do they use instead of leg?
limb
