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It binds to and activates protein kinase A, which then phosphorylates other enzymes.
CREB is a transcription factor whose name is short for cAMP response element-binding protein. It is classically activated by the cAMP intracellular signaling cascade, in which elevated intracellular cAMP levels activate cAMP-dependent protein kinase (PKA). PKA then activates CREB by phosphorylating it on specific serine and threonine admino acid residues, changing the properties of CREB so that it can bind DNA and other proteins to regulate transcription of certain genes.
2nd messengers breakdown because they have great power to proceed the signalling pathway. the pathway continue to give results until 2nd messenger level decreases in cytoplasm e.g., cAMP is a powerful 2nd messenger and stimulates PKA (protein kinase A) PKA proceed pathway but on the same time activates PDE3 (phospodiesterase 3) which inactivates cAMP if this process not happens then there is imbalance of functions e.g., Beta 2-receptors in seminal tract act by cAMP and cause relaxation and alpha 1 receptors act by Ca++ and cause contraction. one system dominates over other at a time and vice versa. now the movement of semen is the combined effect of contractions and relaxations if cAMP level is increased by inhibiting its break down through PDE3 tehn there will be only relaxation and semen cannot move hence failure of ejaculation.
Each hormone is a signal for the cell, that a specific chemical reaction must be done. As the molecules of hormones attach to cell receptors, adenylyl cyclase (transmembrane protein) is activated. Activated Adenylyl cyclase modifies ATP to form cyclic adenine monophosphate (cAMP). cAMP then activates various enzymes that catalyse the necessary reaction. Therefore, cAMP is an intermedium between the hormone and the result (chemical reaction).
There are camps on both sides of Mount Everest: North (Tibet) side camps: Base Camp: 17,000ft --- ABC: 21,300ft --- Camp 1: 23,000ft --- Camp 2: 24,750ft --- Camp 3: 25,600ft --- Camp 4: 27,400ft South (Nepal) side camps: Base Camp: 17,400ft --- Camp 1: 19,600ft --- Camp 2: 20,700ft --- Camp 3: 23,000ft --- Camp 4: 26,100ft
It binds to and activates protein kinase A, which then phosphorylates other enzymes.
CREB is a transcription factor whose name is short for cAMP response element-binding protein. It is classically activated by the cAMP intracellular signaling cascade, in which elevated intracellular cAMP levels activate cAMP-dependent protein kinase (PKA). PKA then activates CREB by phosphorylating it on specific serine and threonine admino acid residues, changing the properties of CREB so that it can bind DNA and other proteins to regulate transcription of certain genes.
2nd messengers breakdown because they have great power to proceed the signalling pathway. the pathway continue to give results until 2nd messenger level decreases in cytoplasm e.g., cAMP is a powerful 2nd messenger and stimulates PKA (protein kinase A) PKA proceed pathway but on the same time activates PDE3 (phospodiesterase 3) which inactivates cAMP if this process not happens then there is imbalance of functions e.g., Beta 2-receptors in seminal tract act by cAMP and cause relaxation and alpha 1 receptors act by Ca++ and cause contraction. one system dominates over other at a time and vice versa. now the movement of semen is the combined effect of contractions and relaxations if cAMP level is increased by inhibiting its break down through PDE3 tehn there will be only relaxation and semen cannot move hence failure of ejaculation.
The Map is located in the Explorer's Camp. Once you have the map you need to collect the flags to activate each of the places on the map. Walk to each area on the map to find the flags.
Each hormone is a signal for the cell, that a specific chemical reaction must be done. As the molecules of hormones attach to cell receptors, adenylyl cyclase (transmembrane protein) is activated. Activated Adenylyl cyclase modifies ATP to form cyclic adenine monophosphate (cAMP). cAMP then activates various enzymes that catalyse the necessary reaction. Therefore, cAMP is an intermedium between the hormone and the result (chemical reaction).
- In the absence of precise information about the mechanisms that regulate gene expression in eukaryotes, many models were proposed. One of the more popular early models known as Britten Davidson model or gene battery model was that given by R.J. Britten and E.H.Davidson in 1969. This model even though widely accepted, is only a theoretical model and lacks sound practical proof. The model predicts the presence of four types of sequences.Producer gen: It is comparable to a structural gene in prokaryotes. It produces pre mRNA, which after processing becomes mRNA. Its expression is under the control of many receptor sites.Receptor site (gene):It is comparable to the operator in bacterial operon. At least one such receptor site is assumed to be present adjacent to each producer gene. A specific receptor site is activated when a specific activator RNA or an activator protein, a product of integrator gene, complexes with it.Integrator gene:Integrator gene is comparable to regulator gene and is responsible for the synthesis of an activator RNA molecule that may not give rise to proteins before it activates the receptor site. At least one integrator gene is present adjacent to each sensor site.Sensor site:A sensor site regulates activity of an integrator gene which can be transcribed only when the sensor site is activated. The sensor sites are also regulatory sequences that are recognized by external stimuli, e.g. hormones, temperatureAccording to the Britten Davidson model, specific sensor genes represent sequence-specific binding sites (similar to CAP­-cAMP binding site in the E. coil) that respond to a specific signal. When sensor genes receive the appropriate signals, they activate the transcription of the adjacent integrator genes. The integrator gene products will then interact in a sequence specific manner with receptor genes.Britten and Davidson proposed that the integrator gene products are activator RNAs that interact directly with the receptor genes to trigger the transcription of the continuous producer genes.It is also proposed that receptor sites and integrator genes may be repeated a number of times so as to control the activity of a large number of genes in the same cell. Repetition of receptor ensures that the same activator recognizes all of them and in this way several enzymes of one metabolic pathway are simultaneously synthesized.Transcription of the same gene may be needed in different developmental stages. This is achieved by the multiplicity of receptor sites and integrator genes. Each producer gene may have several receptor sites, each responding to one activator. Thus, though a single activator can recognize several genes, different activators may activate the same gene at different times.A set of structural genes controlled by one sensor site is termed as a battery. Sometimes when major changes are needed, it is necessary to activate several sets of genes. If one sensor site is associated with several integrators, it may cause transcription of all integrators simultaneously thus causing transcription of several producer genes through receptor sites.The repetition of integrator genes and receptor sites is consistent with the reports that state that sufficient repeated DNA occurs in the eukaryotic cells. The most attractive features of the Britten and Davidson model is that it provides a plausible reason for the observed pattern of interspersion of moderately repetitive DNA sequences and single copy DNA sequences.Direct evidence indicates that most structural genes are indeed single copy DNA sequences. The adjacent moderately repetitive DNA sequences would contain the various kinds of regulator genes (sensor, integrator and receptor genes).
Second messengers activate other intracellular chemicals to produce the target cell response. Their are five types discovered, one of them is CAMP (cyclic adenosine mono-phosphate)
camp mikell is a camp in toccoa georgia. The camp is a week long. plus, there is a variety of camps sessions such as traditional camp, work camp,mini camp, and performing arts camp. The faith for the camp is episcopallian.
Camp means camp
There are two types of digestion: mechanical (such as chewing), and chemical (involving enzymes.) Enzymes are protein-based, biological catalysts that are specific to a particular molecule. Protease enzymes, for instance, break down proteins, while lipase enzymes digest lipids. Each enzyme has a region called the active site. It is the active site that makes enzymes specific to just one substrate, due to its unique shape. The molecules attach to the active aite, and are broken down. Once the nutrients are digested into their end products, they are small enough to be absorbed into the bloodstream.
worst camp ever do not go to this camp
you can camp but their is no official camp