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There are seven primary causes of aging. They are cell loss, nuclear mutations and epimutations, mitochondrial mutations, extracellular junk, intracellular junk, cellular senescence, and extracellular cross-links.

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9y ago
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2w ago

The underlying cause of cellular effects of aging is believed to be multifactorial, involving a combination of genetic, environmental, and lifestyle factors. Key factors include DNA damage, telomere shortening, mitochondrial dysfunction, cellular senescence, and inflammation. These processes contribute to cellular and tissue dysfunction over time, leading to the overall aging of the organism.

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Q: Underlying cause of the cellular effects of aging?
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Will calorie restriction slow the aging process and why?

Some research suggests that calorie restriction can slow down the aging process by improving cellular repair mechanisms and reducing oxidative stress. By consuming fewer calories, the body produces fewer free radicals which can cause damage to cells and accelerate aging. However, more studies are needed to fully understand the effects of calorie restriction on aging in humans.


How may the degradation of telomeres result in cellular aging?

The degradation of telomeres, which are the protective caps at the ends of chromosomes, results in cellular aging because each time a cell divides, a small portion of the telomere is lost. As telomeres shorten, it eventually reaches a critical length that triggers cell senescence or programmed cell death. This leads to a reduction in the cell's ability to divide and function properly, contributing to the overall aging of tissues and organs.


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Oxidation in the human body refers to the process where molecules lose electrons, leading to the production of free radicals. Free radicals can cause cellular damage and are associated with various diseases, including cancer and aging. Antioxidants help neutralize free radicals and prevent oxidative damage.

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