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Diabetic ketoacidosis (DKA) is a dangerous consequence of type 1 Diabetes and, to a lesser extent, type 2 diabetes. When blood sugar levels are extremely high, acidic molecules called ketones build up to deadly quantities in your body, causing DKA.
DKA occurs when human body does not have enough insulin to convert blood sugar into energy. If this occurs, liver begins to convert fat into energy, releasing ketones into the bloodstream. Ketone high levels in the blood are extremely dangerous.
Because insulin levels don't normally dip so low in people with type 2 diabetes, it's less common, although it can happen. Because persons with type 1 diabetes can't generate their own insulin, DKA could be the earliest sign of the disease.
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What are some of the causes of metabolic acidosis?
-Ketoacidosis, a buildup of keto acids that can result from diabetes mellitus. -Salicylate poisoning, a toxic condition resulting from ingestion of too much aspirin or oil of wintergreen (a substance often found in laboratories) - The ingestion of too much alcohol, which metabolizes to acetic acid -Diarrhea, which results in the loss of bicarbonate with the elimination of intestinal contents - Strenuous exercise, which may cause a buildup of lactic acid from anaerobic muscle metabolism
How does Diabetes Mellitus complicate into Diabetes Ketoacidosis?
diabetes ketoacidocis (DKA) results from relative or absolute insulin deficiency combined with counter regulatory hormone excess (glucagon, catecholamines, cortisol, and growth hormone). Both insulin deficiency and glucagon excess, in particular, are necessary for DKA to develop. The decreased ratio of insulin to glucagon promotes gluconeogenesis, glycogenolysis, and ketone body formation in the liver, as well as increases in substrate delivery from fat and muscle (free fatty acids, amino acids) to the liver.
What produces ketone bodies?
Ketone bodies are produced in the liver when there is insufficient glucose available for energy production. This can happen during fasting, prolonged exercise, low-carbohydrate diets (such as ketogenic diets), or in untreated diabetes mellitus. The process is known as ketogenesis.
When ketone bodies are present in the blood and urine in large amounts it usually indicates increased metabolism of?
When ketone bodies are present in large amounts in the blood and urine, it usually indicates increased metabolism of fats. This can occur during conditions such as fasting, low carbohydrate intake, or uncontrolled diabetes mellitus.
Is there a link between diabetes and increased levels of creatinine in the blood?
Diabetes mellitus has adverse effects on many body systems - the cardiovascular system, the neurological system, the endocrine system (obviously) and the renal system. Over time, diabetes causes damage to the small blood vessels in the kidneys, resulting in nephrosclerosis and nephropathy, which decreases the ability of the kidneys to clear the blood of toxins, water, salts, and acids. The creatinine is a marker physicians use to measure kidney function. Because of the damage to the blood vessels in the kidneys, there is elevated BUN and creatinine.
What process cause for the absence of glucose and amino acids in urine?
The absence of glucose and amino acids in urine is primarily due to their reabsorption in the kidneys. In the renal tubules, glucose and amino acids are reabsorbed from the filtrate back into the bloodstream through specific transport mechanisms, such as sodium-glucose co-transporters and amino acid transporters. This reabsorption process ensures that these essential nutrients are retained in the body rather than excreted. If glucose or amino acids appear in urine, it may indicate a pathological condition, such as diabetes mellitus or renal tubular disorders.
Can phenylalanine cause diabetes?
No, phenylalanine is entirely unrelated to diabetes. Diabetes in its three forms is a metabolic disorder involving insulin, a hormone normally secreted in response to elevated blood sugars. Phenylalanine is an amino acid. Amino acids serve primarily as the building blocks of proteins, among other functions. As an amino acid, phenylalanine has no direct impact on blood sugar and thus has no impact on secretion of insulin or the need for insulin. Of course, amino acids can be converted to glucose via gluconeogenesis under certain physiological conditions, however this would not contribute to the development of diabetes, as it is a highly regulated response to low blood sugar. Type II diabetes can result from chronic elevation of blood sugars.
What is the result of amino acids deficiency?
death
What muscles are overworked soreness is caused by a buildup of what?
when soreness occurs, it is because of a build-up of lactic acids.
What three known diseases are omega 3 fatty acids known to help prevent or minimize?
heart cholesterol diabetes
Does 10 codons result in 30 amino acids?
No, 10 codons do not result in 30 amino acids. Each codon corresponds to a single amino acid, so 10 codons would result in 10 amino acids. The genetic code is read in triplets, where each codon is made up of three nucleotides, but the number of amino acids produced is equal to the number of codons.
What do you do about soreness after a work out?
Soreness is caused by a buildup of certain acids in the muscles. Drink a lot of water, and move around. This will help to flush the acid from your system.
