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An excess of end-product molecules alters the shape of the first enzyme in the pathway and shuts off that metabolic pathway?
Feedback Inhibition
End products of biosynthetic pathways often act to block the initial step in that pathway This phenomenon is called?
metabolic inhibition
What end product from a metabolic pathway binds to an enzyme involved in a reaction at the beginning of the pathway. changing the shape of the active site and preventing the enzyme from?
Feedback inhibition
When a pathway is subject to allosteric feedback inhibition ...?
an accumulation of effectors slows the pathway.
Regulatory device in which the product of a pathway binds to an enzyme early in the pathway?
feedback inhibition
The shutting down of a biochemical pathway caused by a key enzyme's sensitivity to the level of the pathway's product?
Feedback Inhibition
An enzyme citrate synthase in the Krebs cycle is inhibited by ATP What type of inhibition would this be?
Citrate synthase is inhibited by ATP. Obviously, the Krebs cycle produces ATP. This is the first step and one of the major regulatory steps in the pathway. If the cell has plenty of ATP, then it wouldn't need to keep making it, thus the pathway needs to be shut off. ATP inhibits the enzyme to shut off the pathway. This is an example of feedback inhibition (you can also call it negative inhibition or even product inhibition). Feedback inhibition is when the products of a certain biochemical pathway inhibit earlier enzymes, shutting down the pathway.
What is the general features of allosteric regulation using the feedback inhibition?
enzymes situated at key steps in metabolic pathways are modulated by allosteric effectors these effectors are usually produced elsewhere in the pathway effectors may be feed-forward activators or feedback inhibitors kinetics are sigmoid ("S-shaped")
How does feedback inhibition affect enzymes?
An enzyme near the beginning of a metabolic pathway is allosterically inhibited by the end product of the pathway. So the feedback inhibition realizes that once we get to a certin level of something made in the cell, it will become an allosteric enzyme and block production so nothing is overproduced in the cell.
Do you think that feeling of fullness and hunger are examples of feedback inhibition?
The feeling of fullness and hunger are examples of the negative feedback inhibition.
What are some examples of feedback inhibition?
an excess of a product of one reaction causes the enzyme of another reaction to stop working.
How do some inhibitors slow down metabolic pathways when the products of the pathways are not needed but still allow a pathway to proceed when the products are needed?
feedback regulation
