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If the man wears a condom so no sperms ever reach the egg is one way. The other way is to be on the Birth Control pill or other contraceptive hormonal methods that prevents the egg from being released so you simply don't ovulate. If you already had sex unprotected there is the morning after pill you can take up to 3-5 days after sex. The earlier the better effect. Two weeks later you have to take a pregnancy test to see if it worked. The coil also works for up to 5 days.

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Q: What activity during oocyte activation prevents penetration by additional sperm?
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