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What are a woman chance of being a carrier for hemophilia if she phenotypically a normal woman and has phenotypically normal parents but has a hemophiliac brother?
Wiki User
∙ 12y ago
She has 1/2 chance. We can figure out exactly what her parents' genotypes were.
Her brother has a Hemophilia allele that he got from his mom. So their mom has at least 1 Hemophilia allele. If she had 2 then she would have Hemophilia.
The father cannot have a Hemophilia allele because it would have been expressed.
So her chances are 1/2 because her mother has 1 Hemophiliac and 1 normal allele.
Wiki User
∙ 12y ago
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Could two phenotypically normal parents have a child with Hemophilia A?
XhXh - with hemophilia XhXH- carrier of hemophilia
Can a male be a carrier for hemophilia?
The gene for hemophilia is found on the 'X' human chromosome. However it is a recessive gene so if a woman (who has two 'XX' chromosomes) has one bad 'X' and one good 'X' she will not have hemophilia but will be a carrier .If she has female children and their father is not a hemophiliac, then half of her daughters may carry the bad 'X' chromosome but non will manifest the disease.However, if her children are male then her sons will have an 'X' chromosome inherited from her and a 'Y' chromosome inherited form the father and there is a 50% chance that the 'X' chromosome inherited will be the bad one. If the son inherits the bad 'X' he will be a hemophiliac and if he lives to father any daughters then all these daughters will be hemophilia carriers (because they must inherit his (bad) 'X' chromosome).It is possible for a woman to manifest hemophilia if the mother is a carrier and the father is a hemophiliac. In this case it is possible for a daughter to inherit the bad 'X' from the father and the mother's bad 'X' giving the daughter two bad 'X' chromosomes.
What are the offspring of hemophilia?
Hemophilia is passed down from mother to son. It is extremely rare for a woman to have hemophilia. It is necessary, though, for a woman to be a carrier of the disorder for her son to acquire this disorder. Females have two X chromosomes whereas males only have one. When a boy is born, he takes one X chromosome from his mother and one Y chromosome from his father. Therefore, he can only get hemophilia through his mother. Example One: Mother(Carrier)+Father(Non-Affected)=50% chance of their son acquiring the disorder and 50% chance of their daughter being a carrier. Example Two: Mother(Non-Affected)+Father(Hemophiliac)=All sons will be non-affected and all daughters will be carriers.
How did Queen Victoria inherit hemophilia?
There are several possibilities of how she inherited hemophilia, but nobody will ever know for sure. Some possibilities are 1. That she is not the Granddaughter of King George III-meaning she was the biological daughter of a hemophiliac 2. Her mother (Victoria of Sax-Coburg) was a carrier - which turned out to be false.
Is hemophilia co dominant or dominant?
It is very much recessive with only one exception, which is that there is a large portion of women who simply carry the trait but dont actually have it. If you are to procreate with a female carrier than your chances of having a hemophiliac child are still not very high. You can find all the info you need by using a Punnett Square method to figure out the chances of hemophiliac children with 2 parents.
A woman is a carrier for hemophilia what are the chances for sons with hemophilia if the father does not have hemophilia?
Since the gene for Hemophilia is carried on the X chromosome and males pass only their Y chromosome onto their sons, no their sons should not have hemophilia. Of course all daughters of a male with hemophilia will be carriers of the mutation since they with receive his X chromosome, not the Y.
How many children would have hemophilia if the female was a carrier of hemophilia and male was normal?
Hemophilia is passed down from mother to son. It is extremely rare for a woman to have hemophilia. It is necessary, though, for a woman to be a carrier of the disorder for her son to acquire this disorder. Females have two X chromosomes whereas males only have one. When a boy is born, he takes one X chromosome from his mother and one Y chromosome from his father. Therefore, he can only get hemophilia through his mother. Example One: Mother(Carrier)+Father(Non-Affected)=50% chance of their son acquiring the disorder and 50% chance of their daughter being a carrier. Example Two: Mother(Non-Affected)+Father(Hemophiliac)=All sons will be non-affected and all daughters will be carriers.
Can two normal parents produce a hemophiliac son?
Approximately 1/3 of the cases of hemophilia are results of random mutations at the time of conception. Thus it is really not that uncommon for two people with completely standard genetics to have a child with hemophilia. Another possibility is that the mother was a carrier and didn't know. Since Hemophilia is due to a mutation on the X chromosome and females have two X chromosomes, it is possible for her to have no signs or reason to believe that she is a carrier. Even in cases with no family history prior, the spontaneous mutation can effect one of the mother's X chromosomes and then get passed on without her knowing she was a carrier.
Explain why women are carrier's for the disease hemophilia. why do their son's get the disease and not the daughter's?
The gene for it occurs on the female (X) chromosome. All humans have either 2(X) chromosomes (women) or an XY pair (men). So if the man inherits a faulty X then he will have hemophilia, while a woman has a sporting chance that her other X chromosome does not have the fault and is thus protected from the disease. It is however possible for a woman with a hemophiliac father and hemophiliac carrying mother to express the disease if she inherits 2 faulty X chromosomes.
A woman is a carrier for hemophilia what is the chances for sons with hemophilia if the father does not have hemophilia?
There are no hard answers to this, it depends strictly on luck. The statistics are though not very good for their children. Statisically the couple have a chance of having a normal son, a daughter that is a carrier for hemophilia, a daughter with hemophilia and a son with hemophia.
What is the probability that their son has hemophilia?
Hemophilia is passed down from mother to son. It is extremely rare for a woman to have hemophilia. It is necessary, though, for a woman to be a carrier of the disorder for her son to acquire this disorder. Females have two X chromosomes whereas males only have one. When a boy is born, he takes one X chromosome from his mother and one Y chromosome from his father. Therefore, he can only get hemophilia through his mother. Example One: Mother(Carrier)+Father(Non-Affected)=50% chance of their son acquiring the disorder and 50% chance of their daughter being a carrier. Example Two: Mother(Non-Affected)+Father(Hemophiliac)=All sons will be non-affected and all daughters will be carriers.
1 Noah has hemophilia and he marries Patricia who is a carrier for hemophilia. What is the probability that their children will have the disease?
50
