All of the leukodystrophies are caused by either a defective protein component of myelin, or by a malfunctioning enzyme that interacts with one of the protein or lipid constituents
All types of leukodystrophy are genetic (present at conception), progressive, and never spontaneously resolve. None of the leukodystrophies can be cured, and effective treatments are limited.
There was a medical breakthrough in 1991 that saw the advance in medical imaging for leukodystrophies. There have been other major breakthroughs in world of medicine.
These are myelinated fibers just at the junction of the gray matter and the white matter which travel in a tangential, rather than radial, fashion connecting areas of cortex to other areas of cortex. What's special about these U-fibers, and why they are either spared or not in leukodystrophies, is that they comprise the slowest myelinating fibers within the nervous system. These U-fibers begin myelination early in gestation and often aren't completely myelinated until the third or fourth decade of life. Therefore, leukodystrophies in which the pathology is dependent on myelin turnover will demonstrate relative sparing of these fibers as the turnover is extremely slow; while in leukodystrophies which depend on toxic damage to the oligodendroglial cell, subcortical U-fibers are as vulnerable as other myelinated fibers within the nervous system.
The Rabbits Who Caused All the Trouble was created in 1939.
Most of the individual leukodystrophies are rare. The most common type is Canavan disease , with an incidence of about one in 8,000, followed by X-linked adrenoleukodystrophy (XL-ALD), which occurs in one in 40,000 male births
Our son 12 years, has this diagnosis. He has a white matter change in the midline of his cerebellum shown on MRI which has remained essentialy the same over 3 years. Because he has been tested for all other known leukodystrophies and all have come back negative his Dr gave him this label for want of a name. It isn't a known entity yet . Hope this is of some help
False some changes are caused by people not all
The Chinese caused all sorts of problems on the goldfields. Why?
All sound is caused by vibrations in the particles of its medium (solid, liquid, or gas).
Some of them are not all of them are caused by humans
They are caused by a virus.
is caused by aliens