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that depends what you mean by worst, so I have made a couple of different lists for you to compare;

Deaths (percent contribution per year (% out of total deaths each year by all causes e.g car crashes))

5. Diarrheal diseases 3.2%

4. Chronic obstructive pulmonary disease 4.8%

3. HIV/AIDS 4.9%

2. Cerebrovascular diseases 9.7%

1. Ischemic Heart disease 12.6%

Most Likely big Outbreaks this decade (most relevant)

5. Swine Flu

4. Bird flu

3. AIDS

2. Cancer

1. Anthrax

Some of these aren't actually classed as diseases but their status is debatable.

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Q: What are the 5 worst diseases in the world and what have you done about them?
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