Genetic changes that correlate with the pine-oil disinfectant-reduced susceptibility mechanism of Staphylococcus aureus. Lamichhane-Khadka R, Riordan JT, Delgado A, Muthaiyan A, Reynolds TD, Wilkinson BJ, Gustafson JE.
SourceDepartment of Biology, New Mexico State University, Las Cruces, NM 88003-8001, USA. AbstractAIMS:To identify factors associated with the Staphylococcus aureus pine-oil disinfectant-reduced-susceptibility (PD(RS)) mechanism and to describe one possible PD(RS) model.
METHODS AND RESULTS:Comparative genomic sequencing (CGS) and microarray analysis were utilized to detect mutations and transcriptome alterations that occur in a S. aureus PD(RS) mutant. Mutant analysis, antimicrobial gradient plates, growth studies and 3-hydroxy-3-methylglutaryl coenzyme A synthase assays were then performed to confirm the biological consequences of the 'omics' alterations detected in a PD(RS) mutant. CGS uncovered three mutations in a PD(RS) mutant in a(n): alcohol dehydrogenase (adh), catabolite control protein A (ccpA) and an NADPH-flavin oxidoreductase (frp). These mutations lead to increased growth rates; increased transcription of an NAD-dependent D-lactate dehydrogenase gene (ddh); and increased flux through the mevalonate pathway. PD(RS) mutants demonstrated reduced susceptibility to bacitracin and farnesol, and one PD(RS) mutant displayed upregulation of bacA, a bacitracin-resistance gene. Collectively, this evidence demonstrates altered undecaprenol metabolism in PD(RS) mutants.
CONCLUSIONS:The PD(RS) mechanism proposed results from increased catabolic capabilities and increased flux through the mevalonate pathway as well as altered bactoprenol physiology.
SIGNIFICANCE AND IMPACT OF THE STUDY:A novel mechanism that bacteria utilize to overcome the killing effects of PD formulations is proposed that is unique from the PD(RS) mechanism of the enterobacteraciae.
Pine nut oil is pressed from pine nuts; olive oil is pressed from olives. Pine nut oil is much more expensive than olive oil. Olive oil is used in many foods, from salads and pasta to breads and other baked goods, while pine nut oil is used in a few specialty recipes.
An essential oil carries a distinctive scent of the plant from which it was extracted. Rosemary oil stimulates hair growth and is considered a strengthening tonic, while pine oil has stimulating effects on the adrenal cortex.
we priduce pine oil,our company is glorychem co.,ltd in China. rh@ronghuachem.com
which store available extra virgin pine nut oil in Dubai
Pine-Sol originally contained pine oil, though it is now a mixture of everything but.
Effects of hash oil
The address of the Caddo Pine Island Oil Historical Society is: Po Box 897, Oil City, LA 71061
No. They are completely different. Olive oil is pressed from olives. Siberian oil is pressed from pine nuts (hence the full name of Siberian Pine Nut Oil).
When you purchase balsamic vinegar, you do not get the oil in the vinegar. However, it is possible to purchase a pine nut oil and balsamic vinegar salad dressing.
its from a treein Germany i think
There are certain bacteria that actually eat oil
8-10% pine oil, alkyl alcohol ethoxylates, sodium petroleum sulfonate and isopropanol. I'm not sure of the elemental abbreviation of pine oil... Po? I'd just say it's 2LeMOnY 2BtRuE!