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Tannins, which are actually no longer considered anti-nutrients, but instead have anti-inflammatory, anti-ulcer and anti-oxidant properties. They are only toxic are very large quantities. Boiling will remove the tannins.

It can (may or may not) contain these as well:

Saponins, though I was unable to determine if it is medicagenic acid, which appears to be the main saponin that is an anti-nutrient. Human's rarely suffer any severe toxic effects from saponins. They put them in some medications.

Flavenoids, which are antibacterial and have been shown in studies to reduce inflammation, to reduce occurrence of two types of cancer and to have antioxidant effects. There is a list of positive effects on the fetus when taken during pregnancy, including prevention of Allergies, but also a list of possible negative effects. The studies have been too few to be conclusive. The most research has been done on cardiovascular disease with a long list of positive effects. 36 Trials have been done or are now in progress. Research is very encouraging.

Alkaloids can be present in varying amounts.

Cyanogenic glycosides, which are in a lot of nuts, seeds and legumes. These cyanogenics are considered "the best phytochemical." They are toxic in high doses, so they must be taken in proper ratios. The seed inside the fruit you are eating is safe for humans. Taking seeds from a bunch of fruit and eating them all at once is not safe.
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Q: What are the antinutritional factors of avocado pear seed?
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