They are postulated to be 1) excess secretion of dopamine, 2) deficiency of serotonin, and 3) deficiency of norepinephrine (among others).
Psychosis in schizophrenia and perhaps schizophreniform disorder appears to be related to abnormalities in the structure and chemistry of the brain, and appears to have strong genetic links
What are three ways the brain is related to mental abnormalities
A biological psychologist would say that people with schizophrenia act like they do because of abnormalities in the brain. Hallucinations might be attributed to abnormalities of the temporal lobe. Breakdown of the frontal lobe may cause disorganized behavior.
Drug use, a family member with schizophrenia or a related disorder, adolescence (in men) and being in your mid-twenties (in women), and your father being old when you were born are risk factors for schizophrenia.
Schizophrenia has no effect on brain weight.
Genetic abnormalities
There is no known pathogen recognize as a cause of schizophrenia. However, there may be biochemical or anatomical abnormalities in some cases.
A brain scan cannot detect schizophrenia, although many people with schizophrenia do have abnormal brain scans. The brain damage is not apparent until the disease has already progressed far enough to show clear signs of schizophrenia.
Paranoid schizophrenia is a disease of the brain.
Schizophrenia mainly affects the brain.
Evidence suggests that schizophrenia is a physical disorder of the brain.
Schizophrenia damages the frontal and temporal lobes and the vesicles.