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Proteins are extremely sensitive to heat because the sudden rise of temperature breaks its hydrogen bonds. The sensitivity of the side chains and its three-dimensional structure also contributes to its reaction to extreme heat.
enzymes
By simply afecting the bonds ( hbonds . ionic bonds and hydrophobic interactions )
affected by temperature or pH cause the protein denature .
Internal temperature or pH changes can disrupt the homeostasis of an organism by affecting the functioning of enzymes and proteins, which are sensitive to changes in their environment. These changes can alter the rate of biochemical reactions and disrupt the overall balance within the organism. Organisms have mechanisms in place, such as sweating or shivering in response to temperature changes, or buffering systems to maintain stable pH levels, to regulate these variables and restore homeostasis.
Hydrogen bonds
Changes in pH or temperature decrease enzyme activity because bonds b reak and the enzyme returns to it's PRIMARY structure. (not tertiary)
Proteins are extremely sensitive to heat because the sudden rise of temperature breaks its hydrogen bonds. The sensitivity of the side chains and its three-dimensional structure also contributes to its reaction to extreme heat.
enzymes
By simply afecting the bonds ( hbonds . ionic bonds and hydrophobic interactions )
By simply afecting the bonds ( hbonds . ionic bonds and hydrophobic interactions )
The temperature optimum can be affected by pH if the pH chosen for a particular experiment deviates from the pH optimum for invertase
affected by temperature or pH cause the protein denature .
That is sort of a broad question. Some never change...Oils, for instance. If you boil distilled water it will show a pH of 7 but it will, over time absorb CO2 from the air if you leave it sit out uncovered. The CO2 will form carbonic acid and cause the pH to drop.
Internal temperature or pH changes can disrupt the homeostasis of an organism by affecting the functioning of enzymes and proteins, which are sensitive to changes in their environment. These changes can alter the rate of biochemical reactions and disrupt the overall balance within the organism. Organisms have mechanisms in place, such as sweating or shivering in response to temperature changes, or buffering systems to maintain stable pH levels, to regulate these variables and restore homeostasis.
excess cofactor
There factors include: -Ionic strength The number of ions and charges present affect the ion activity coefficient and hence the activity of charges species in the solution -Dilution of buffer with water The pH will change and this will affect the ion activity coefficient. The activity of charges species in the solution is hence affected since water itself can act as an acid or base. -Temperature The effect of temperature on weak acids and its conjugate base as a buffer is small due to small changes in its ionization constant Ka as a function of the temperature. As for a weak base and its conjugate acid, the pH is constant only if the temperature is constant. If the temperature fluctuates, the pH changes according to the changes in pKw for water and pKw is very susceptible to temperature changes.